Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3518c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3516 and Rv3517 are separated by 95 nucleotidesRv3517 and Rv3518c are separated by 54 nucleotidesRv3518c and Rv3519 are separated by 28 nucleotidesRv3519 and Rv3520c are separated by 64 nucleotides Rv3516: Rv3516 - Possible enoyl-CoA hydratase EchA19 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 3,952,544 to 3,953,335 Rv3516 Rv3517: Rv3517 - Conserved hypothetical protein, at 3,953,431 to 3,954,270 Rv3517 Rv3518c: Rv3518c - Probable cytochrome P450 monooxygenase 142 Cyp142, at 3,954,325 to 3,955,521 Rv3518c Rv3519: Rv3519 - Unknown protein, at 3,955,550 to 3,956,260 Rv3519 Rv3520c: Rv3520c - Possible coenzyme F420-dependent oxidoreductase, at 3,956,325 to 3,957,368 Rv3520c Position (kb) 3954 3955 3956Strain fitness (log2 ratio) -1 0 1 2at 3953.503 kb on + strandat 3953.504 kb on - strandat 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.528 kb on - strand, within Rv3517at 3953.583 kb on - strand, within Rv3517at 3953.677 kb on + strand, within Rv3517at 3953.678 kb on - strand, within Rv3517at 3953.678 kb on - strand, within Rv3517at 3953.763 kb on + strand, within Rv3517at 3953.764 kb on - strand, within Rv3517at 3953.928 kb on + strand, within Rv3517at 3954.046 kb on + strand, within Rv3517at 3954.709 kb on + strand, within Rv3518cat 3954.811 kb on - strand, within Rv3518cat 3955.385 kb on + strand, within Rv3518cat 3955.386 kb on - strand, within Rv3518cat 3955.479 kb on - strandat 3955.537 kb on + strandat 3955.550 kb on - strandat 3955.697 kb on + strand, within Rv3519at 3955.773 kb on - strand, within Rv3519at 3956.054 kb on + strand, within Rv3519at 3956.054 kb on + strand, within Rv3519at 3956.055 kb on - strand, within Rv3519at 3956.159 kb on + strand, within Rv3519at 3956.293 kb on - strandat 3956.515 kb on - strand, within Rv3520cat 3956.515 kb on - strand, within Rv3520cat 3956.515 kb on - strand, within Rv3520c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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3,953,503 + +0.1
3,953,504 - +0.2
3,953,527 + Rv3517 0.11 -0.9
3,953,527 + Rv3517 0.11 -0.6
3,953,527 + Rv3517 0.11 +0.1
3,953,527 + Rv3517 0.11 +0.5
3,953,527 + Rv3517 0.11 -0.2
3,953,527 + Rv3517 0.11 -0.6
3,953,527 + Rv3517 0.11 +0.8
3,953,527 + Rv3517 0.11 -0.0
3,953,528 - Rv3517 0.12 -0.2
3,953,583 - Rv3517 0.18 +0.1
3,953,677 + Rv3517 0.29 -0.4
3,953,678 - Rv3517 0.29 +0.6
3,953,678 - Rv3517 0.29 -0.4
3,953,763 + Rv3517 0.40 -0.4
3,953,764 - Rv3517 0.40 -1.0
3,953,928 + Rv3517 0.59 -0.1
3,954,046 + Rv3517 0.73 +0.5
3,954,709 + Rv3518c 0.32 -0.1
3,954,811 - Rv3518c 0.41 +0.7
3,955,385 + Rv3518c 0.89 +1.8
3,955,386 - Rv3518c 0.89 +0.2
3,955,479 - -0.5
3,955,537 + -0.3
3,955,550 - -0.0
3,955,697 + Rv3519 0.21 -0.3
3,955,773 - Rv3519 0.31 +0.2
3,956,054 + Rv3519 0.71 +0.6
3,956,054 + Rv3519 0.71 -0.1
3,956,055 - Rv3519 0.71 +0.0
3,956,159 + Rv3519 0.86 +1.5
3,956,293 - +0.4
3,956,515 - Rv3520c 0.18 +1.4
3,956,515 - Rv3520c 0.18 +0.6
3,956,515 - Rv3520c 0.18 -0.1

Or see this region's nucleotide sequence