Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3103c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3101c and Rv3102c are separated by 0 nucleotidesRv3102c and Rv3103c are separated by 43 nucleotidesRv3103c and Rv3104c are separated by 1 nucleotidesRv3104c and Rv3105c overlap by 11 nucleotides Rv3101c: Rv3101c - Putative cell division protein FtsX (septation component-transport integral membrane protein ABC transporter), at 3,469,786 to 3,470,679 Rv3101c Rv3102c: Rv3102c - Putative cell division ATP-binding protein FtsE (septation component-transport ATP-binding protein ABC transporter), at 3,470,680 to 3,471,369 Rv3102c Rv3103c: Rv3103c - Hypothetical proline-rich protein, at 3,471,413 to 3,471,850 Rv3103c Rv3104c: Rv3104c - Possible conserved transmembrane protein, at 3,471,852 to 3,472,778 Rv3104c Rv3105c: Rv3105c - Probable peptide chain release factor 2 PrfB (RF-2), at 3,472,768 to 3,473,904 Rv3105c Position (kb) 3471 3472Strain fitness (log2 ratio) -1 0 1 2at 3470.566 kb on - strand, within Rv3101cat 3470.660 kb on - strandat 3470.831 kb on - strand, within Rv3102cat 3470.848 kb on - strand, within Rv3102cat 3471.078 kb on - strand, within Rv3102cat 3471.385 kb on + strandat 3471.441 kb on + strandat 3471.442 kb on - strandat 3471.657 kb on + strand, within Rv3103cat 3471.657 kb on + strand, within Rv3103cat 3471.658 kb on - strand, within Rv3103cat 3471.733 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.745 kb on - strand, within Rv3103cat 3471.745 kb on - strand, within Rv3103cat 3472.481 kb on - strand, within Rv3104cat 3472.495 kb on + strand, within Rv3104cat 3472.496 kb on - strand, within Rv3104cat 3472.534 kb on - strand, within Rv3104cat 3472.727 kb on + strandat 3472.728 kb on - strandat 3472.744 kb on - strandat 3472.780 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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3,470,566 - Rv3101c 0.87 +0.8
3,470,660 - -0.8
3,470,831 - Rv3102c 0.22 +0.2
3,470,848 - Rv3102c 0.24 -0.1
3,471,078 - Rv3102c 0.58 +0.8
3,471,385 + -0.2
3,471,441 + -0.3
3,471,442 - +0.1
3,471,657 + Rv3103c 0.56 +0.3
3,471,657 + Rv3103c 0.56 +0.1
3,471,658 - Rv3103c 0.56 +0.4
3,471,733 + Rv3103c 0.73 -0.5
3,471,735 + Rv3103c 0.74 +0.3
3,471,735 + Rv3103c 0.74 +0.4
3,471,735 + Rv3103c 0.74 +0.6
3,471,736 - Rv3103c 0.74 +0.3
3,471,736 - Rv3103c 0.74 -0.0
3,471,736 - Rv3103c 0.74 +1.0
3,471,745 - Rv3103c 0.76 +1.2
3,471,745 - Rv3103c 0.76 -0.2
3,472,481 - Rv3104c 0.68 +0.5
3,472,495 + Rv3104c 0.69 +0.2
3,472,496 - Rv3104c 0.69 +0.4
3,472,534 - Rv3104c 0.74 +2.4
3,472,727 + -0.2
3,472,728 - +0.2
3,472,744 - -0.4
3,472,780 - -0.3

Or see this region's nucleotide sequence