Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2900c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2899c and Rv2900c overlap by 1 nucleotidesRv2900c and Rv2901c are separated by 57 nucleotidesRv2901c and Rv2902c are separated by 53 nucleotides Rv2899c: Rv2899c - Possible FdhD protein homolog, at 3,208,576 to 3,209,406 Rv2899c Rv2900c: Rv2900c - Possible formate dehydrogenase H FdhF (formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide) (formate dehydrogenase-H alpha subunit) (FDH-H), at 3,209,406 to 3,211,745 Rv2900c Rv2901c: Rv2901c - Conserved protein, at 3,211,803 to 3,212,108 Rv2901c Rv2902c: Rv2902c - Probable ribonuclease HII protein RnhB (RNase HII), at 3,212,162 to 3,212,956 Rv2902c Position (kb) 3209 3210 3211 3212Strain fitness (log2 ratio) -2 -1 0 1 2at 3208.435 kb on - strandat 3208.485 kb on + strandat 3208.485 kb on + strandat 3208.578 kb on - strandat 3209.069 kb on + strand, within Rv2899cat 3209.139 kb on - strand, within Rv2899cat 3209.510 kb on - strandat 3209.540 kb on - strandat 3209.734 kb on + strand, within Rv2900cat 3209.734 kb on + strand, within Rv2900cat 3209.905 kb on + strand, within Rv2900cat 3209.906 kb on - strand, within Rv2900cat 3209.956 kb on + strand, within Rv2900cat 3210.465 kb on + strand, within Rv2900cat 3210.465 kb on + strand, within Rv2900cat 3210.466 kb on - strand, within Rv2900cat 3210.590 kb on + strand, within Rv2900cat 3210.716 kb on - strand, within Rv2900cat 3211.225 kb on + strand, within Rv2900cat 3211.225 kb on + strand, within Rv2900cat 3211.226 kb on - strand, within Rv2900cat 3211.226 kb on - strand, within Rv2900cat 3211.226 kb on - strand, within Rv2900cat 3211.283 kb on - strand, within Rv2900cat 3211.434 kb on - strand, within Rv2900cat 3211.544 kb on + strandat 3211.617 kb on + strandat 3211.618 kb on - strandat 3211.741 kb on + strandat 3211.741 kb on + strandat 3211.741 kb on + strandat 3211.741 kb on + strandat 3211.742 kb on - strandat 3211.742 kb on - strandat 3211.742 kb on - strandat 3211.804 kb on + strandat 3211.804 kb on + strandat 3211.805 kb on - strandat 3211.805 kb on - strandat 3211.900 kb on + strand, within Rv2901cat 3211.943 kb on - strand, within Rv2901cat 3211.993 kb on + strand, within Rv2901cat 3212.013 kb on + strand, within Rv2901cat 3212.014 kb on - strand, within Rv2901cat 3212.084 kb on - strandat 3212.163 kb on + strandat 3212.164 kb on - strandat 3212.164 kb on - strandat 3212.328 kb on + strand, within Rv2902cat 3212.329 kb on - strand, within Rv2902cat 3212.389 kb on - strand, within Rv2902cat 3212.611 kb on + strand, within Rv2902cat 3212.611 kb on + strand, within Rv2902cat 3212.612 kb on - strand, within Rv2902cat 3212.612 kb on - strand, within Rv2902cat 3212.612 kb on - strand, within Rv2902cat 3212.679 kb on + strand, within Rv2902cat 3212.680 kb on - strand, within Rv2902c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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3,208,435 - -0.2
3,208,485 + -0.1
3,208,485 + -0.3
3,208,578 - +0.3
3,209,069 + Rv2899c 0.59 +0.2
3,209,139 - Rv2899c 0.68 -0.6
3,209,510 - -0.7
3,209,540 - -0.3
3,209,734 + Rv2900c 0.14 +0.3
3,209,734 + Rv2900c 0.14 -0.5
3,209,905 + Rv2900c 0.21 +0.6
3,209,906 - Rv2900c 0.21 +0.0
3,209,956 + Rv2900c 0.24 +0.1
3,210,465 + Rv2900c 0.45 -0.3
3,210,465 + Rv2900c 0.45 +0.6
3,210,466 - Rv2900c 0.45 +0.1
3,210,590 + Rv2900c 0.51 +1.0
3,210,716 - Rv2900c 0.56 +0.2
3,211,225 + Rv2900c 0.78 -0.0
3,211,225 + Rv2900c 0.78 +0.8
3,211,226 - Rv2900c 0.78 +0.1
3,211,226 - Rv2900c 0.78 -0.5
3,211,226 - Rv2900c 0.78 -1.2
3,211,283 - Rv2900c 0.80 +1.1
3,211,434 - Rv2900c 0.87 -0.2
3,211,544 + +0.4
3,211,617 + +2.3
3,211,618 - -1.4
3,211,741 + +1.1
3,211,741 + -0.0
3,211,741 + -0.6
3,211,741 + -0.2
3,211,742 - -0.1
3,211,742 - -0.2
3,211,742 - +0.8
3,211,804 + +0.0
3,211,804 + +0.1
3,211,805 - +0.7
3,211,805 - -0.1
3,211,900 + Rv2901c 0.32 -0.4
3,211,943 - Rv2901c 0.46 -0.0
3,211,993 + Rv2901c 0.62 +0.4
3,212,013 + Rv2901c 0.69 +0.2
3,212,014 - Rv2901c 0.69 -0.4
3,212,084 - -0.2
3,212,163 + -2.6
3,212,164 - -0.2
3,212,164 - -0.6
3,212,328 + Rv2902c 0.21 -0.2
3,212,329 - Rv2902c 0.21 -0.9
3,212,389 - Rv2902c 0.29 +0.3
3,212,611 + Rv2902c 0.56 +0.2
3,212,611 + Rv2902c 0.56 +0.7
3,212,612 - Rv2902c 0.57 -2.1
3,212,612 - Rv2902c 0.57 +0.4
3,212,612 - Rv2902c 0.57 +2.6
3,212,679 + Rv2902c 0.65 -0.4
3,212,680 - Rv2902c 0.65 -1.4

Or see this region's nucleotide sequence