Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2812

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2810c and Rv2811 overlap by 4 nucleotidesRv2811 and Rv2812 are separated by 70 nucleotidesRv2812 and Rv2813 overlap by 4 nucleotides Rv2810c: Rv2810c - Probable transposase, at 3,115,741 to 3,116,142 Rv2810c Rv2811: Rv2811 - Conserved hypothetical protein, at 3,116,139 to 3,116,747 Rv2811 Rv2812: Rv2812 - Probable transposase, at 3,116,818 to 3,118,227 Rv2812 Rv2813: Rv2813 - Conserved hypothetical protein, at 3,118,224 to 3,119,036 Rv2813 Position (kb) 3116 3117 3118 3119Strain fitness (log2 ratio) -1 0 1at 3115.837 kb on + strand, within Rv2810cat 3115.957 kb on + strand, within Rv2810cat 3115.958 kb on - strand, within Rv2810cat 3115.958 kb on - strand, within Rv2810cat 3115.960 kb on + strand, within Rv2810cat 3117.359 kb on - strand, within Rv2812at 3117.902 kb on - strand, within Rv2812at 3118.246 kb on - strandat 3118.639 kb on - strand, within Rv2813at 3118.828 kb on - strand, within Rv2813

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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3,115,837 + Rv2810c 0.24 -0.1
3,115,957 + Rv2810c 0.54 +0.3
3,115,958 - Rv2810c 0.54 -0.2
3,115,958 - Rv2810c 0.54 +0.3
3,115,960 + Rv2810c 0.54 +1.3
3,117,359 - Rv2812 0.38 -0.5
3,117,902 - Rv2812 0.77 -0.5
3,118,246 - +0.2
3,118,639 - Rv2813 0.51 -0.2
3,118,828 - Rv2813 0.74 -0.6

Or see this region's nucleotide sequence