Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2573

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2572c and Rv2573 are separated by 239 nucleotidesRv2573 and Rv2574 are separated by 22 nucleotidesRv2574 and Rv2575 are separated by 29 nucleotides Rv2572c: Rv2572c - Probable aspartyl-tRNA synthetase AspS (aspartate--tRNA ligase) (ASPRS) (aspartic acid translase), at 2,896,013 to 2,897,803 Rv2572c Rv2573: Rv2573 - Conserved hypothetical protein, at 2,898,043 to 2,898,783 Rv2573 Rv2574: Rv2574 - Conserved protein, at 2,898,806 to 2,899,309 Rv2574 Rv2575: Rv2575 - Possible conserved membrane glycine rich protein, at 2,899,339 to 2,900,220 Rv2575 Position (kb) 2898 2899Strain fitness (log2 ratio) -1 0 1 2at 2897.837 kb on + strandat 2897.838 kb on - strandat 2898.453 kb on + strand, within Rv2573at 2898.453 kb on + strand, within Rv2573at 2898.453 kb on + strand, within Rv2573at 2898.453 kb on + strand, within Rv2573at 2898.453 kb on + strand, within Rv2573at 2898.453 kb on + strand, within Rv2573at 2898.454 kb on - strand, within Rv2573at 2898.520 kb on + strand, within Rv2573at 2898.793 kb on + strandat 2898.793 kb on + strandat 2898.793 kb on + strandat 2898.800 kb on + strandat 2898.801 kb on - strandat 2898.809 kb on + strandat 2898.809 kb on + strandat 2898.809 kb on + strandat 2898.810 kb on - strandat 2898.854 kb on + strandat 2898.854 kb on + strandat 2898.855 kb on - strandat 2899.271 kb on + strandat 2899.271 kb on + strandat 2899.272 kb on - strandat 2899.274 kb on - strandat 2899.524 kb on - strand, within Rv2575at 2899.646 kb on - strand, within Rv2575at 2899.682 kb on + strand, within Rv2575

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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2,897,837 + +1.1
2,897,838 - +0.2
2,898,453 + Rv2573 0.55 +1.8
2,898,453 + Rv2573 0.55 -1.1
2,898,453 + Rv2573 0.55 +0.1
2,898,453 + Rv2573 0.55 -1.4
2,898,453 + Rv2573 0.55 -0.3
2,898,453 + Rv2573 0.55 -0.6
2,898,454 - Rv2573 0.55 +0.5
2,898,520 + Rv2573 0.64 -0.3
2,898,793 + -1.3
2,898,793 + -0.1
2,898,793 + -0.3
2,898,800 + -0.0
2,898,801 - -0.5
2,898,809 + -0.2
2,898,809 + -0.6
2,898,809 + -0.2
2,898,810 - -0.3
2,898,854 + -1.3
2,898,854 + +0.5
2,898,855 - +0.1
2,899,271 + -0.3
2,899,271 + +0.5
2,899,272 - -0.2
2,899,274 - -0.1
2,899,524 - Rv2575 0.21 -0.4
2,899,646 - Rv2575 0.35 +0.6
2,899,682 + Rv2575 0.39 +0.5

Or see this region's nucleotide sequence