Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2551c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2549c and Rv2550c overlap by 4 nucleotidesRv2550c and Rv2551c are separated by 410 nucleotidesRv2551c and Rv2552c are separated by 11 nucleotidesRv2552c and Rv2553c overlap by 4 nucleotides Rv2549c: Rv2549c - Possible toxin VapC20, at 2,869,727 to 2,870,122 Rv2549c Rv2550c: Rv2550c - Possible antitoxin VapB20, at 2,870,119 to 2,870,364 Rv2550c Rv2551c: Rv2551c - Conserved hypothetical protein, at 2,870,775 to 2,871,194 Rv2551c Rv2552c: Rv2552c - Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase), at 2,871,206 to 2,872,015 Rv2552c Rv2553c: Rv2553c - Probable conserved membrane protein, at 2,872,012 to 2,873,265 Rv2553c Position (kb) 2870 2871 2872Strain fitness (log2 ratio) -1 0 1 2at 2869.782 kb on + strand, within Rv2549cat 2869.782 kb on + strand, within Rv2549cat 2869.782 kb on + strand, within Rv2549cat 2869.782 kb on + strand, within Rv2549cat 2869.782 kb on + strand, within Rv2549cat 2869.783 kb on - strand, within Rv2549cat 2869.783 kb on - strand, within Rv2549cat 2869.783 kb on - strand, within Rv2549cat 2869.783 kb on - strand, within Rv2549cat 2869.901 kb on + strand, within Rv2549cat 2869.901 kb on + strand, within Rv2549cat 2869.901 kb on + strand, within Rv2549cat 2869.901 kb on + strand, within Rv2549cat 2870.240 kb on + strand, within Rv2550cat 2870.321 kb on + strand, within Rv2550cat 2870.321 kb on + strand, within Rv2550cat 2870.322 kb on - strand, within Rv2550cat 2870.322 kb on - strand, within Rv2550cat 2870.322 kb on - strand, within Rv2550cat 2870.322 kb on - strand, within Rv2550cat 2870.521 kb on + strandat 2870.550 kb on + strandat 2870.561 kb on + strandat 2871.019 kb on + strand, within Rv2551cat 2871.020 kb on - strand, within Rv2551cat 2871.208 kb on - strandat 2871.208 kb on - strandat 2872.125 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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2,869,782 + Rv2549c 0.14 +0.1
2,869,782 + Rv2549c 0.14 +0.2
2,869,782 + Rv2549c 0.14 -0.3
2,869,782 + Rv2549c 0.14 -0.4
2,869,782 + Rv2549c 0.14 +0.3
2,869,783 - Rv2549c 0.14 +0.7
2,869,783 - Rv2549c 0.14 +1.8
2,869,783 - Rv2549c 0.14 +1.3
2,869,783 - Rv2549c 0.14 +0.3
2,869,901 + Rv2549c 0.44 -0.5
2,869,901 + Rv2549c 0.44 -0.3
2,869,901 + Rv2549c 0.44 +0.5
2,869,901 + Rv2549c 0.44 +1.8
2,870,240 + Rv2550c 0.49 -0.5
2,870,321 + Rv2550c 0.82 +0.1
2,870,321 + Rv2550c 0.82 -0.1
2,870,322 - Rv2550c 0.83 -0.3
2,870,322 - Rv2550c 0.83 +0.5
2,870,322 - Rv2550c 0.83 -0.7
2,870,322 - Rv2550c 0.83 +0.0
2,870,521 + -0.3
2,870,550 + -0.2
2,870,561 + +1.2
2,871,019 + Rv2551c 0.58 +0.5
2,871,020 - Rv2551c 0.58 +0.4
2,871,208 - +0.0
2,871,208 - -0.1
2,872,125 - -0.3

Or see this region's nucleotide sequence