Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2510c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2508c and Rv2509 are separated by 84 nucleotidesRv2509 and Rv2510c are separated by 3 nucleotidesRv2510c and Rv2511 are separated by 67 nucleotidesRv2511 and GFF2615 are separated by 49 nucleotides Rv2508c: Rv2508c - Probable conserved integral membrane leucine and alanine rich protein, at 2,823,256 to 2,824,593 Rv2508c Rv2509: Rv2509 - Probable short-chain type dehydrogenase/reductase, at 2,824,678 to 2,825,484 Rv2509 Rv2510c: Rv2510c - Conserved protein, at 2,825,488 to 2,827,089 Rv2510c Rv2511: Rv2511 - Oligoribonuclease Orn, at 2,827,157 to 2,827,804 Rv2511 GFF2615 - tRNA-His, at 2,827,854 to 2,827,926 GFF2615 Position (kb) 2825 2826 2827 2828Strain fitness (log2 ratio) -1 0 1 2at 2824.606 kb on - strandat 2824.606 kb on - strandat 2824.658 kb on + strandat 2824.659 kb on - strandat 2824.659 kb on - strandat 2825.482 kb on + strandat 2825.737 kb on + strand, within Rv2510cat 2825.957 kb on + strand, within Rv2510cat 2825.958 kb on - strand, within Rv2510cat 2826.255 kb on + strand, within Rv2510cat 2826.256 kb on - strand, within Rv2510cat 2826.615 kb on + strand, within Rv2510cat 2827.029 kb on - strandat 2827.090 kb on - strandat 2827.090 kb on - strandat 2827.103 kb on + strandat 2827.103 kb on + strandat 2827.103 kb on + strandat 2827.144 kb on + strandat 2828.006 kb on + strandat 2828.006 kb on + strandat 2828.007 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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2,824,606 - +0.2
2,824,606 - -0.8
2,824,658 + -0.5
2,824,659 - -0.2
2,824,659 - +0.1
2,825,482 + -0.2
2,825,737 + Rv2510c 0.16 +1.8
2,825,957 + Rv2510c 0.29 +0.1
2,825,958 - Rv2510c 0.29 -1.0
2,826,255 + Rv2510c 0.48 -0.2
2,826,256 - Rv2510c 0.48 -0.2
2,826,615 + Rv2510c 0.70 -1.3
2,827,029 - -0.1
2,827,090 - -0.1
2,827,090 - -0.2
2,827,103 + -0.2
2,827,103 + -0.7
2,827,103 + -0.4
2,827,144 + -0.0
2,828,006 + -0.1
2,828,006 + +0.7
2,828,007 - -0.4

Or see this region's nucleotide sequence