Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1959c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1957 and Rv1958c overlap by 112 nucleotidesRv1958c and Rv1959c are separated by 48 nucleotidesRv1959c and Rv1960c overlap by 4 nucleotidesRv1960c and Rv1961 overlap by 14 nucleotidesRv1961 and Rv1962c are separated by 159 nucleotides Rv1957: Rv1957 - Hypothetical protein, at 2,202,584 to 2,203,129 Rv1957 Rv1958c: Rv1958c - Hypothetical protein, at 2,203,018 to 2,203,632 Rv1958c Rv1959c: Rv1959c - Possible toxin ParE1, at 2,203,681 to 2,203,977 Rv1959c Rv1960c: Rv1960c - Possible antitoxin ParD1, at 2,203,974 to 2,204,225 Rv1960c Rv1961: Rv1961 - Hypothetical protein, at 2,204,212 to 2,204,706 Rv1961 Rv1962c: Rv1962c - Possible toxin VapC35. Contains PIN domain., at 2,204,866 to 2,205,273 Rv1962c Position (kb) 2203 2204Strain fitness (log2 ratio) -2 -1 0 1 2at 2202.729 kb on - strand, within Rv1957at 2202.729 kb on - strand, within Rv1957at 2202.773 kb on - strand, within Rv1957at 2203.065 kb on + strandat 2203.065 kb on + strandat 2203.065 kb on + strandat 2203.066 kb on - strandat 2203.178 kb on - strand, within Rv1958cat 2203.178 kb on - strand, within Rv1958cat 2203.438 kb on - strand, within Rv1958cat 2203.529 kb on - strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.546 kb on + strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.547 kb on - strand, within Rv1958cat 2203.877 kb on + strand, within Rv1959cat 2203.877 kb on + strand, within Rv1959cat 2203.877 kb on + strand, within Rv1959cat 2203.878 kb on - strand, within Rv1959cat 2203.910 kb on + strand, within Rv1959cat 2203.910 kb on + strand, within Rv1959cat 2203.911 kb on - strand, within Rv1959cat 2203.911 kb on - strand, within Rv1959cat 2203.964 kb on + strandat 2203.964 kb on + strandat 2204.003 kb on + strand, within Rv1960cat 2204.003 kb on + strand, within Rv1960cat 2204.188 kb on + strand, within Rv1960cat 2204.188 kb on + strand, within Rv1960cat 2204.219 kb on + strandat 2204.249 kb on + strandat 2204.259 kb on + strandat 2204.389 kb on + strand, within Rv1961at 2204.390 kb on - strand, within Rv1961at 2204.401 kb on + strand, within Rv1961at 2204.402 kb on - strand, within Rv1961at 2204.402 kb on - strand, within Rv1961at 2204.402 kb on - strand, within Rv1961at 2204.638 kb on + strand, within Rv1961at 2204.728 kb on + strandat 2204.783 kb on - strandat 2204.787 kb on + strandat 2204.923 kb on - strand, within Rv1962cat 2204.936 kb on + strand, within Rv1962cat 2204.937 kb on - strand, within Rv1962c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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2,202,729 - Rv1957 0.27 +0.2
2,202,729 - Rv1957 0.27 +1.1
2,202,773 - Rv1957 0.35 +0.2
2,203,065 + +0.0
2,203,065 + +0.3
2,203,065 + +0.0
2,203,066 - +0.1
2,203,178 - Rv1958c 0.26 -0.1
2,203,178 - Rv1958c 0.26 -0.4
2,203,438 - Rv1958c 0.68 +0.3
2,203,529 - Rv1958c 0.83 +1.8
2,203,546 + Rv1958c 0.86 +2.2
2,203,546 + Rv1958c 0.86 -1.7
2,203,546 + Rv1958c 0.86 +0.1
2,203,546 + Rv1958c 0.86 -0.0
2,203,547 - Rv1958c 0.86 -0.7
2,203,547 - Rv1958c 0.86 +0.2
2,203,547 - Rv1958c 0.86 -0.6
2,203,547 - Rv1958c 0.86 -0.9
2,203,877 + Rv1959c 0.66 +0.2
2,203,877 + Rv1959c 0.66 -1.8
2,203,877 + Rv1959c 0.66 -0.6
2,203,878 - Rv1959c 0.66 -0.3
2,203,910 + Rv1959c 0.77 -0.0
2,203,910 + Rv1959c 0.77 -0.2
2,203,911 - Rv1959c 0.77 -0.1
2,203,911 - Rv1959c 0.77 -0.1
2,203,964 + -0.3
2,203,964 + -0.4
2,204,003 + Rv1960c 0.12 +0.1
2,204,003 + Rv1960c 0.12 -0.0
2,204,188 + Rv1960c 0.85 -0.1
2,204,188 + Rv1960c 0.85 -0.3
2,204,219 + +0.2
2,204,249 + -0.0
2,204,259 + -0.3
2,204,389 + Rv1961 0.36 +0.3
2,204,390 - Rv1961 0.36 -0.3
2,204,401 + Rv1961 0.38 -0.1
2,204,402 - Rv1961 0.38 +0.7
2,204,402 - Rv1961 0.38 -0.4
2,204,402 - Rv1961 0.38 +0.4
2,204,638 + Rv1961 0.86 -0.4
2,204,728 + -0.2
2,204,783 - -0.5
2,204,787 + -0.2
2,204,923 - Rv1962c 0.14 +0.1
2,204,936 + Rv1962c 0.17 -0.3
2,204,937 - Rv1962c 0.17 +0.5

Or see this region's nucleotide sequence