Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1951c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1949c and Rv1950c overlap by 37 nucleotidesRv1950c and Rv1951c are separated by 0 nucleotidesRv1951c and Rv1952 are separated by 239 nucleotidesRv1952 and Rv1953 overlap by 4 nucleotidesRv1953 and Rv1954c overlap by 27 nucleotides Rv1949c: Rv1949c - Conserved hypothetical protein, at 2,199,075 to 2,200,034 Rv1949c Rv1950c: Rv1950c - Conserved hypothetical protein, at 2,199,998 to 2,200,189 Rv1950c Rv1951c: Rv1951c - Conserved hypothetical protein, at 2,200,190 to 2,200,486 Rv1951c Rv1952: Rv1952 - Possible antitoxin VapB14, at 2,200,726 to 2,200,941 Rv1952 Rv1953: Rv1953 - Possible toxin VapC14, at 2,200,938 to 2,201,249 Rv1953 Rv1954c: Rv1954c - Hypothetical protein, at 2,201,223 to 2,201,744 Rv1954c Rv1954A: Rv1954A - Hypothetical protein, at 2,201,277 to 2,201,579 Rv1954A Position (kb) 2200 2201Strain fitness (log2 ratio) -2 -1 0 1 2at 2199.267 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.307 kb on - strand, within Rv1949cat 2199.499 kb on + strand, within Rv1949cat 2199.499 kb on + strand, within Rv1949cat 2199.546 kb on + strand, within Rv1949cat 2199.547 kb on - strand, within Rv1949cat 2199.547 kb on - strand, within Rv1949cat 2199.698 kb on + strand, within Rv1949cat 2199.698 kb on + strand, within Rv1949cat 2199.721 kb on - strand, within Rv1949cat 2199.907 kb on + strand, within Rv1949cat 2199.907 kb on + strand, within Rv1949cat 2199.908 kb on - strand, within Rv1949cat 2199.908 kb on - strand, within Rv1949cat 2199.999 kb on + strandat 2200.000 kb on - strandat 2200.000 kb on - strandat 2200.125 kb on + strand, within Rv1950cat 2200.126 kb on - strand, within Rv1950cat 2200.126 kb on - strand, within Rv1950cat 2200.169 kb on - strand, within Rv1950cat 2200.191 kb on + strandat 2200.192 kb on - strandat 2200.254 kb on + strand, within Rv1951cat 2200.255 kb on - strand, within Rv1951cat 2200.255 kb on - strand, within Rv1951cat 2200.449 kb on - strand, within Rv1951cat 2200.499 kb on + strandat 2200.510 kb on + strandat 2200.545 kb on - strandat 2200.617 kb on - strandat 2200.687 kb on - strandat 2200.691 kb on - strandat 2200.694 kb on - strandat 2200.694 kb on - strandat 2200.694 kb on - strandat 2200.694 kb on - strandat 2200.763 kb on + strand, within Rv1952at 2200.859 kb on + strand, within Rv1952at 2200.944 kb on + strandat 2200.944 kb on + strandat 2200.944 kb on + strandat 2200.945 kb on - strandat 2201.122 kb on + strand, within Rv1953at 2201.123 kb on - strand, within Rv1953at 2201.155 kb on + strand, within Rv1953at 2201.155 kb on + strand, within Rv1953at 2201.155 kb on + strand, within Rv1953at 2201.155 kb on + strand, within Rv1953at 2201.155 kb on + strand, within Rv1953at 2201.156 kb on - strand, within Rv1953at 2201.156 kb on - strand, within Rv1953at 2201.156 kb on - strand, within Rv1953at 2201.225 kb on - strandat 2201.236 kb on + strandat 2201.236 kb on + strandat 2201.236 kb on + strandat 2201.324 kb on + strandat 2201.324 kb on + strandat 2201.324 kb on + strandat 2201.325 kb on - strandat 2201.411 kb on + strandat 2201.412 kb on - strandat 2201.412 kb on - strandat 2201.417 kb on + strandat 2201.417 kb on + strandat 2201.417 kb on + strandat 2201.417 kb on + strandat 2201.417 kb on + strandat 2201.418 kb on - strandat 2201.430 kb on - strandat 2201.430 kb on - strandat 2201.454 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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2,199,267 + Rv1949c 0.20 +0.2
2,199,306 + Rv1949c 0.24 -1.2
2,199,306 + Rv1949c 0.24 +0.6
2,199,306 + Rv1949c 0.24 +0.7
2,199,307 - Rv1949c 0.24 -1.0
2,199,499 + Rv1949c 0.44 -0.0
2,199,499 + Rv1949c 0.44 -0.2
2,199,546 + Rv1949c 0.49 -0.2
2,199,547 - Rv1949c 0.49 -0.1
2,199,547 - Rv1949c 0.49 +0.0
2,199,698 + Rv1949c 0.65 -0.2
2,199,698 + Rv1949c 0.65 -1.2
2,199,721 - Rv1949c 0.67 -0.3
2,199,907 + Rv1949c 0.87 -0.6
2,199,907 + Rv1949c 0.87 -0.0
2,199,908 - Rv1949c 0.87 -0.5
2,199,908 - Rv1949c 0.87 -0.2
2,199,999 + -0.1
2,200,000 - +0.3
2,200,000 - +0.1
2,200,125 + Rv1950c 0.66 +2.1
2,200,126 - Rv1950c 0.67 -2.2
2,200,126 - Rv1950c 0.67 -0.4
2,200,169 - Rv1950c 0.89 -0.8
2,200,191 + -0.2
2,200,192 - -0.2
2,200,254 + Rv1951c 0.22 +0.1
2,200,255 - Rv1951c 0.22 +1.4
2,200,255 - Rv1951c 0.22 +0.1
2,200,449 - Rv1951c 0.87 +0.3
2,200,499 + -0.2
2,200,510 + -1.1
2,200,545 - -0.2
2,200,617 - +0.6
2,200,687 - +0.1
2,200,691 - +0.3
2,200,694 - -0.5
2,200,694 - +1.6
2,200,694 - +0.8
2,200,694 - -0.2
2,200,763 + Rv1952 0.17 -0.0
2,200,859 + Rv1952 0.62 -0.3
2,200,944 + +0.3
2,200,944 + -0.9
2,200,944 + +0.4
2,200,945 - -0.4
2,201,122 + Rv1953 0.59 +0.4
2,201,123 - Rv1953 0.59 -0.0
2,201,155 + Rv1953 0.70 -1.1
2,201,155 + Rv1953 0.70 -0.2
2,201,155 + Rv1953 0.70 +0.6
2,201,155 + Rv1953 0.70 +0.0
2,201,155 + Rv1953 0.70 -0.7
2,201,156 - Rv1953 0.70 +0.5
2,201,156 - Rv1953 0.70 -0.5
2,201,156 - Rv1953 0.70 +0.1
2,201,225 - -0.0
2,201,236 + -0.3
2,201,236 + -1.0
2,201,236 + +0.6
2,201,324 + +0.1
2,201,324 + +1.3
2,201,324 + +0.5
2,201,325 - -0.4
2,201,411 + +0.5
2,201,412 - -0.3
2,201,412 - -1.0
2,201,417 + +0.6
2,201,417 + -0.2
2,201,417 + +1.3
2,201,417 + -0.5
2,201,417 + -0.4
2,201,418 - +0.2
2,201,430 - -0.2
2,201,430 - -0.5
2,201,454 + +0.0

Or see this region's nucleotide sequence