Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1046c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1045 and Rv1046c are separated by 149 nucleotidesRv1046c and Rv1047 are separated by 194 nucleotides Rv1045: Rv1045 - Hypothetical protein, at 1,167,673 to 1,168,554 Rv1045 Rv1046c: Rv1046c - Hypothetical protein, at 1,168,704 to 1,169,228 Rv1046c Rv1047: Rv1047 - Probable transposase, at 1,169,423 to 1,170,670 Rv1047 Position (kb) 1168 1169 1170Strain fitness (log2 ratio) -2 -1 0 1at 1167.716 kb on + strandat 1167.737 kb on + strandat 1167.944 kb on + strand, within Rv1045at 1167.945 kb on - strand, within Rv1045at 1168.035 kb on + strand, within Rv1045at 1168.035 kb on + strand, within Rv1045at 1168.035 kb on + strand, within Rv1045at 1168.075 kb on + strand, within Rv1045at 1168.250 kb on + strand, within Rv1045at 1168.251 kb on - strand, within Rv1045at 1168.373 kb on + strand, within Rv1045at 1168.373 kb on + strand, within Rv1045at 1168.442 kb on - strand, within Rv1045at 1168.442 kb on - strand, within Rv1045at 1168.442 kb on - strand, within Rv1045at 1168.608 kb on + strandat 1168.683 kb on + strandat 1168.705 kb on + strandat 1168.706 kb on - strandat 1168.706 kb on - strandat 1168.836 kb on + strand, within Rv1046cat 1168.837 kb on - strand, within Rv1046cat 1168.837 kb on - strand, within Rv1046cat 1168.926 kb on + strand, within Rv1046cat 1169.288 kb on + strandat 1169.291 kb on + strandat 1169.291 kb on + strandat 1169.292 kb on - strandat 1169.292 kb on - strandat 1169.302 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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1,167,716 + -0.0
1,167,737 + -0.3
1,167,944 + Rv1045 0.31 -0.1
1,167,945 - Rv1045 0.31 -0.3
1,168,035 + Rv1045 0.41 +0.4
1,168,035 + Rv1045 0.41 -1.0
1,168,035 + Rv1045 0.41 -0.1
1,168,075 + Rv1045 0.46 -0.1
1,168,250 + Rv1045 0.65 -0.5
1,168,251 - Rv1045 0.66 +0.2
1,168,373 + Rv1045 0.79 -0.5
1,168,373 + Rv1045 0.79 -0.3
1,168,442 - Rv1045 0.87 -0.9
1,168,442 - Rv1045 0.87 -0.4
1,168,442 - Rv1045 0.87 -0.6
1,168,608 + -0.3
1,168,683 + -0.2
1,168,705 + -0.8
1,168,706 - -0.3
1,168,706 - -0.3
1,168,836 + Rv1046c 0.25 -0.2
1,168,837 - Rv1046c 0.25 +1.3
1,168,837 - Rv1046c 0.25 +0.1
1,168,926 + Rv1046c 0.42 +0.7
1,169,288 + +0.3
1,169,291 + -1.9
1,169,291 + +0.5
1,169,292 - -0.3
1,169,292 - +0.2
1,169,302 - -0.7

Or see this region's nucleotide sequence