Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0950c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0949 and Rv0950c are separated by 80 nucleotidesRv0950c and Rv0951 are separated by 309 nucleotides Rv0949: Rv0949 - Probable ATP-dependent DNA helicase II UvrD1, at 1,058,260 to 1,060,575 Rv0949 Rv0950c: Rv0950c - Conserved hypothetical protein, at 1,060,656 to 1,061,654 Rv0950c Rv0951: Rv0951 - Probable succinyl-CoA synthetase (beta chain) SucC (SCS-beta), at 1,061,964 to 1,063,127 Rv0951 Position (kb) 1060 1061 1062Strain fitness (log2 ratio) -2 -1 0 1at 1060.453 kb on + strandat 1060.574 kb on + strandat 1060.666 kb on + strandat 1060.667 kb on - strandat 1060.679 kb on + strandat 1060.852 kb on + strand, within Rv0950cat 1060.853 kb on - strand, within Rv0950cat 1060.996 kb on - strand, within Rv0950cat 1060.996 kb on - strand, within Rv0950cat 1061.271 kb on - strand, within Rv0950cat 1061.489 kb on - strand, within Rv0950cat 1061.512 kb on - strand, within Rv0950cat 1061.560 kb on - strandat 1061.560 kb on - strandat 1061.673 kb on - strandat 1061.757 kb on + strandat 1061.757 kb on + strandat 1061.925 kb on + strandat 1061.925 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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1,060,453 + +1.3
1,060,574 + +0.6
1,060,666 + -0.5
1,060,667 - +0.8
1,060,679 + +0.0
1,060,852 + Rv0950c 0.20 +0.7
1,060,853 - Rv0950c 0.20 +0.2
1,060,996 - Rv0950c 0.34 +1.3
1,060,996 - Rv0950c 0.34 +0.7
1,061,271 - Rv0950c 0.62 -0.0
1,061,489 - Rv0950c 0.83 +0.5
1,061,512 - Rv0950c 0.86 +0.2
1,061,560 - +0.5
1,061,560 - -1.0
1,061,673 - +0.9
1,061,757 + -0.2
1,061,757 + -0.4
1,061,925 + -0.3
1,061,925 + -1.8

Or see this region's nucleotide sequence