Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0726c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0724A and Rv0725c overlap by 328 nucleotidesRv0725c and Rv0726c are separated by 92 nucleotidesRv0726c and Rv0727c are separated by 202 nucleotidesRv0727c and Rv0728c overlap by 4 nucleotides Rv0724A: Rv0724A - Conserved hypothetical protein, at 817,531 to 817,866 Rv0724A Rv0725c: Rv0725c - Conserved hypothetical protein, at 817,539 to 818,444 Rv0725c Rv0726c: Rv0726c - Possible S-adenosylmethionine-dependent methyltransferase, at 818,537 to 819,640 Rv0726c Rv0727c: Rv0727c - Possible L-fuculose phosphate aldolase FucA (L-fuculose-1-phosphate aldolase), at 819,843 to 820,499 Rv0727c Rv0728c: Rv0728c - Possible D-3-phosphoglycerate dehydrogenase SerA2 (phosphoglycerate dehydrogenase) (PGDH), at 820,496 to 821,476 Rv0728c Position (kb) 818 819 820Strain fitness (log2 ratio) -1 0 1 2 3at 817.622 kb on - strandat 817.700 kb on + strandat 817.701 kb on - strandat 817.880 kb on - strand, within Rv0725cat 817.975 kb on + strand, within Rv0725cat 818.171 kb on - strand, within Rv0725cat 818.256 kb on - strand, within Rv0725cat 818.453 kb on + strandat 818.453 kb on + strandat 818.686 kb on - strand, within Rv0726cat 818.686 kb on - strand, within Rv0726cat 818.721 kb on + strand, within Rv0726cat 818.721 kb on + strand, within Rv0726cat 818.722 kb on - strand, within Rv0726cat 818.832 kb on + strand, within Rv0726cat 818.833 kb on - strand, within Rv0726cat 818.862 kb on + strand, within Rv0726cat 818.970 kb on - strand, within Rv0726cat 819.055 kb on - strand, within Rv0726cat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.680 kb on - strandat 819.680 kb on - strandat 819.752 kb on + strandat 819.792 kb on - strandat 819.792 kb on - strandat 819.844 kb on + strandat 819.872 kb on - strandat 820.102 kb on + strand, within Rv0727cat 820.132 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.258 kb on - strand, within Rv0727cat 820.263 kb on + strand, within Rv0727cat 820.264 kb on - strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.355 kb on - strand, within Rv0727cat 820.508 kb on + strandat 820.508 kb on + strandat 820.509 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
remove
817,622 - -0.5
817,700 + -0.4
817,701 - +0.4
817,880 - Rv0725c 0.38 +0.0
817,975 + Rv0725c 0.48 -0.6
818,171 - Rv0725c 0.70 +0.1
818,256 - Rv0725c 0.79 +0.4
818,453 + +0.5
818,453 + +0.3
818,686 - Rv0726c 0.13 -1.2
818,686 - Rv0726c 0.13 -1.5
818,721 + Rv0726c 0.17 +0.9
818,721 + Rv0726c 0.17 +3.0
818,722 - Rv0726c 0.17 +0.4
818,832 + Rv0726c 0.27 +0.7
818,833 - Rv0726c 0.27 +1.5
818,862 + Rv0726c 0.29 +1.0
818,970 - Rv0726c 0.39 +0.7
819,055 - Rv0726c 0.47 +0.9
819,633 + +0.8
819,633 + +1.2
819,633 + +0.9
819,633 + +0.8
819,633 + +0.8
819,633 + +0.8
819,633 + +0.9
819,633 + +0.3
819,634 - +0.5
819,634 - +0.7
819,634 - +0.5
819,634 - +1.4
819,634 - -1.2
819,634 - +1.4
819,634 - -0.3
819,634 - +0.5
819,680 - -0.9
819,680 - -1.4
819,752 + -0.1
819,792 - -0.7
819,792 - -1.1
819,844 + -0.4
819,872 - -0.4
820,102 + Rv0727c 0.39 -0.2
820,132 + Rv0727c 0.44 +0.2
820,257 + Rv0727c 0.63 +0.8
820,257 + Rv0727c 0.63 +0.6
820,257 + Rv0727c 0.63 -0.0
820,257 + Rv0727c 0.63 -1.5
820,258 - Rv0727c 0.63 -0.3
820,263 + Rv0727c 0.64 +0.1
820,264 - Rv0727c 0.64 -0.1
820,323 + Rv0727c 0.73 +0.0
820,323 + Rv0727c 0.73 -0.2
820,323 + Rv0727c 0.73 +0.1
820,323 + Rv0727c 0.73 -0.3
820,355 - Rv0727c 0.78 +0.4
820,508 + -0.3
820,508 + -0.0
820,509 - +0.6

Or see this region's nucleotide sequence