Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0275c

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0273c and Rv0274 are separated by 96 nucleotidesRv0274 and Rv0275c overlap by 71 nucleotidesRv0275c and Rv0276 are separated by 89 nucleotides Rv0273c: Rv0273c - Possible transcriptional regulatory protein, at 329,705 to 330,325 Rv0273c Rv0274: Rv0274 - Conserved protein, at 330,422 to 331,003 Rv0274 Rv0275c: Rv0275c - Possible transcriptional regulatory protein (possibly TetR-family), at 330,933 to 331,658 Rv0275c Rv0276: Rv0276 - Conserved hypothetical protein, at 331,748 to 332,668 Rv0276 Position (kb) 330 331 332Strain fitness (log2 ratio) -1 0 1 2at 330.036 kb on + strand, within Rv0273cat 330.175 kb on - strand, within Rv0273cat 330.180 kb on + strand, within Rv0273cat 330.180 kb on + strand, within Rv0273cat 330.860 kb on + strand, within Rv0274at 330.860 kb on + strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.865 kb on - strand, within Rv0274at 331.080 kb on + strand, within Rv0275cat 331.081 kb on - strand, within Rv0275cat 331.490 kb on - strand, within Rv0275cat 331.705 kb on - strandat 332.017 kb on + strand, within Rv0276at 332.021 kb on + strand, within Rv0276at 332.022 kb on - strand, within Rv0276at 332.129 kb on + strand, within Rv0276at 332.152 kb on - strand, within Rv0276at 332.177 kb on + strand, within Rv0276at 332.180 kb on - strand, within Rv0276at 332.378 kb on + strand, within Rv0276at 332.379 kb on - strand, within Rv0276

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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330,036 + Rv0273c 0.53 -0.2
330,175 - Rv0273c 0.76 +0.2
330,180 + Rv0273c 0.76 -0.3
330,180 + Rv0273c 0.76 +0.6
330,860 + Rv0274 0.75 +0.7
330,860 + Rv0274 0.75 +1.2
330,861 - Rv0274 0.75 -0.3
330,861 - Rv0274 0.75 +0.5
330,861 - Rv0274 0.75 +0.5
330,861 - Rv0274 0.75 +1.8
330,865 - Rv0274 0.76 +0.8
331,080 + Rv0275c 0.20 +1.8
331,081 - Rv0275c 0.20 +0.1
331,490 - Rv0275c 0.77 +0.8
331,705 - -0.5
332,017 + Rv0276 0.29 -0.1
332,021 + Rv0276 0.30 +0.6
332,022 - Rv0276 0.30 -0.5
332,129 + Rv0276 0.41 +0.6
332,152 - Rv0276 0.44 +1.6
332,177 + Rv0276 0.47 -0.1
332,180 - Rv0276 0.47 -0.1
332,378 + Rv0276 0.68 -0.2
332,379 - Rv0276 0.69 -0.6

Or see this region's nucleotide sequence