Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0218

Experiment: 7H9 with Sulfaquinoxaline 0.097 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0217c and Rv0218 are separated by 92 nucleotidesRv0218 and Rv0219 are separated by 1 nucleotidesRv0219 and Rv0220 are separated by 9 nucleotides Rv0216: Rv0216 - Double hotdog hydratase, at 258,913 to 259,926 Rv0216 Rv0217c: Rv0217c - Possible esterase LipW, at 259,923 to 260,831 Rv0217c Rv0218: Rv0218 - Probable conserved transmembrane protein, at 260,924 to 262,252 Rv0218 Rv0219: Rv0219 - Probable conserved transmembrane protein, at 262,254 to 262,802 Rv0219 Rv0220: Rv0220 - Probable esterase LipC, at 262,812 to 264,023 Rv0220 Position (kb) 260 261 262 263Strain fitness (log2 ratio) -1 0 1 2at 259.924 kb on + strandat 259.935 kb on - strandat 259.974 kb on - strandat 260.050 kb on - strand, within Rv0217cat 260.157 kb on + strand, within Rv0217cat 260.209 kb on + strand, within Rv0217cat 260.209 kb on + strand, within Rv0217cat 260.209 kb on + strand, within Rv0217cat 260.210 kb on - strand, within Rv0217cat 260.255 kb on - strand, within Rv0217cat 260.302 kb on + strand, within Rv0217cat 260.455 kb on + strand, within Rv0217cat 260.584 kb on - strand, within Rv0217cat 260.702 kb on + strand, within Rv0217cat 261.131 kb on + strand, within Rv0218at 261.131 kb on + strand, within Rv0218at 261.131 kb on + strand, within Rv0218at 261.132 kb on - strand, within Rv0218at 261.133 kb on + strand, within Rv0218at 261.134 kb on - strand, within Rv0218at 261.134 kb on - strand, within Rv0218at 261.431 kb on + strand, within Rv0218at 261.432 kb on - strand, within Rv0218at 261.438 kb on - strand, within Rv0218at 261.511 kb on + strand, within Rv0218at 261.888 kb on + strand, within Rv0218at 262.048 kb on + strand, within Rv0218at 262.344 kb on + strand, within Rv0219at 262.551 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.723 kb on - strand, within Rv0219at 262.868 kb on - strandat 262.889 kb on + strandat 262.890 kb on - strandat 263.246 kb on - strand, within Rv0220

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfaquinoxaline 0.097 mM
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259,924 + +0.3
259,935 - +0.8
259,974 - -0.5
260,050 - Rv0217c 0.14 -0.4
260,157 + Rv0217c 0.26 +0.3
260,209 + Rv0217c 0.31 -0.0
260,209 + Rv0217c 0.31 -0.4
260,209 + Rv0217c 0.31 +0.2
260,210 - Rv0217c 0.32 +0.1
260,255 - Rv0217c 0.37 +0.3
260,302 + Rv0217c 0.42 -0.2
260,455 + Rv0217c 0.59 +0.6
260,584 - Rv0217c 0.73 -0.4
260,702 + Rv0217c 0.86 -0.6
261,131 + Rv0218 0.16 +0.5
261,131 + Rv0218 0.16 -0.5
261,131 + Rv0218 0.16 -0.1
261,132 - Rv0218 0.16 +2.4
261,133 + Rv0218 0.16 -0.0
261,134 - Rv0218 0.16 +0.3
261,134 - Rv0218 0.16 +0.0
261,431 + Rv0218 0.38 +1.1
261,432 - Rv0218 0.38 +0.2
261,438 - Rv0218 0.39 +0.1
261,511 + Rv0218 0.44 -0.1
261,888 + Rv0218 0.73 +1.3
262,048 + Rv0218 0.85 +1.8
262,344 + Rv0219 0.16 -0.8
262,551 + Rv0219 0.54 -1.3
262,632 + Rv0219 0.69 +0.4
262,632 + Rv0219 0.69 -1.2
262,632 + Rv0219 0.69 -1.4
262,723 - Rv0219 0.85 +1.3
262,868 - -0.2
262,889 + +0.7
262,890 - -0.2
263,246 - Rv0220 0.36 -0.8

Or see this region's nucleotide sequence