Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3885c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3884c and Rv3885c are separated by 69 nucleotidesRv3885c and Rv3886c overlap by 4 nucleotides Rv3884c: Rv3884c - ESX conserved component EccA2. ESX-2 type VII secretion system protein. Probable CbxX/CfqX family protein., at 4,364,979 to 4,366,838 Rv3884c Rv3885c: Rv3885c - ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein., at 4,366,908 to 4,368,521 Rv3885c Rv3886c: Rv3886c - Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-2), at 4,368,518 to 4,370,170 Rv3886c Position (kb) 4366 4367 4368 4369Strain fitness (log2 ratio) -2 -1 0 1at 4366.120 kb on + strand, within Rv3884cat 4366.120 kb on + strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.388 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.424 kb on - strand, within Rv3884cat 4366.443 kb on + strand, within Rv3884cat 4366.444 kb on - strand, within Rv3884cat 4366.806 kb on + strandat 4367.473 kb on - strand, within Rv3885cat 4367.740 kb on + strand, within Rv3885cat 4368.168 kb on + strand, within Rv3885cat 4368.333 kb on + strand, within Rv3885cat 4368.370 kb on - strandat 4368.415 kb on - strandat 4368.598 kb on + strandat 4368.695 kb on - strand, within Rv3886cat 4368.852 kb on + strand, within Rv3886cat 4368.853 kb on - strand, within Rv3886cat 4368.887 kb on - strand, within Rv3886cat 4368.887 kb on - strand, within Rv3886cat 4369.053 kb on + strand, within Rv3886cat 4369.054 kb on - strand, within Rv3886cat 4369.131 kb on + strand, within Rv3886cat 4369.131 kb on + strand, within Rv3886cat 4369.132 kb on - strand, within Rv3886cat 4369.132 kb on - strand, within Rv3886cat 4369.213 kb on - strand, within Rv3886c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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4,366,120 + Rv3884c 0.61 +0.1
4,366,120 + Rv3884c 0.61 +1.6
4,366,388 - Rv3884c 0.76 -1.2
4,366,388 - Rv3884c 0.76 -0.4
4,366,388 - Rv3884c 0.76 -0.1
4,366,388 - Rv3884c 0.76 -0.2
4,366,388 - Rv3884c 0.76 -0.5
4,366,424 - Rv3884c 0.78 +0.4
4,366,424 - Rv3884c 0.78 -0.3
4,366,424 - Rv3884c 0.78 -0.3
4,366,443 + Rv3884c 0.79 +0.0
4,366,444 - Rv3884c 0.79 +0.0
4,366,806 + -0.1
4,367,473 - Rv3885c 0.35 -0.4
4,367,740 + Rv3885c 0.52 +0.9
4,368,168 + Rv3885c 0.78 +0.1
4,368,333 + Rv3885c 0.88 +1.6
4,368,370 - -0.7
4,368,415 - +0.0
4,368,598 + +0.8
4,368,695 - Rv3886c 0.11 +1.1
4,368,852 + Rv3886c 0.20 +0.1
4,368,853 - Rv3886c 0.20 +0.1
4,368,887 - Rv3886c 0.22 +0.0
4,368,887 - Rv3886c 0.22 +0.0
4,369,053 + Rv3886c 0.32 -0.2
4,369,054 - Rv3886c 0.32 -0.4
4,369,131 + Rv3886c 0.37 -0.1
4,369,131 + Rv3886c 0.37 -0.1
4,369,132 - Rv3886c 0.37 -1.3
4,369,132 - Rv3886c 0.37 -2.2
4,369,213 - Rv3886c 0.42 +0.3

Or see this region's nucleotide sequence