Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3842c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3840 and Rv3841 are separated by 197 nucleotidesRv3841 and Rv3842c are separated by 14 nucleotidesRv3842c and Rv3843c are separated by 5 nucleotides Rv3840: Rv3840 - Possible transcriptional regulatory protein, at 4,313,567 to 4,313,980 Rv3840 Rv3841: Rv3841 - Bacterioferritin BfrB, at 4,314,178 to 4,314,723 Rv3841 Rv3842c: Rv3842c - Probable glycerophosphoryl diester phosphodiesterase GlpQ1 (glycerophosphodiester phosphodiesterase), at 4,314,738 to 4,315,562 Rv3842c Rv3843c: Rv3843c - Probable conserved transmembrane protein, at 4,315,568 to 4,316,596 Rv3843c Position (kb) 4314 4315 4316Strain fitness (log2 ratio) -1 0 1 2at 4313.894 kb on + strand, within Rv3840at 4313.894 kb on + strand, within Rv3840at 4313.929 kb on - strand, within Rv3840at 4313.979 kb on - strandat 4314.030 kb on - strandat 4314.087 kb on + strandat 4314.088 kb on - strandat 4314.091 kb on - strandat 4314.146 kb on + strandat 4314.262 kb on + strand, within Rv3841at 4314.411 kb on - strand, within Rv3841at 4314.644 kb on + strand, within Rv3841at 4314.644 kb on + strand, within Rv3841at 4314.645 kb on - strand, within Rv3841at 4314.721 kb on + strandat 4314.721 kb on + strandat 4314.722 kb on - strandat 4314.722 kb on - strandat 4314.803 kb on + strandat 4314.804 kb on - strandat 4314.851 kb on - strand, within Rv3842cat 4314.916 kb on + strand, within Rv3842cat 4314.917 kb on - strand, within Rv3842cat 4314.989 kb on - strand, within Rv3842cat 4315.129 kb on - strand, within Rv3842cat 4315.320 kb on + strand, within Rv3842cat 4315.320 kb on + strand, within Rv3842cat 4315.468 kb on + strand, within Rv3842cat 4315.469 kb on - strand, within Rv3842cat 4315.481 kb on + strandat 4315.481 kb on + strandat 4315.481 kb on + strandat 4315.481 kb on + strandat 4315.569 kb on + strandat 4315.570 kb on - strandat 4315.570 kb on - strandat 4316.003 kb on - strand, within Rv3843cat 4316.003 kb on - strand, within Rv3843cat 4316.340 kb on - strand, within Rv3843c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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4,313,894 + Rv3840 0.79 +0.0
4,313,894 + Rv3840 0.79 +0.2
4,313,929 - Rv3840 0.87 -0.6
4,313,979 - +0.4
4,314,030 - -0.1
4,314,087 + +1.9
4,314,088 - -0.5
4,314,091 - +0.8
4,314,146 + -0.2
4,314,262 + Rv3841 0.15 +0.0
4,314,411 - Rv3841 0.43 -0.4
4,314,644 + Rv3841 0.85 -0.0
4,314,644 + Rv3841 0.85 -0.3
4,314,645 - Rv3841 0.86 -0.6
4,314,721 + +0.0
4,314,721 + -0.0
4,314,722 - -0.8
4,314,722 - -0.7
4,314,803 + +0.7
4,314,804 - +0.1
4,314,851 - Rv3842c 0.14 +0.1
4,314,916 + Rv3842c 0.22 +1.6
4,314,917 - Rv3842c 0.22 +1.9
4,314,989 - Rv3842c 0.30 +0.2
4,315,129 - Rv3842c 0.47 +1.3
4,315,320 + Rv3842c 0.71 +1.9
4,315,320 + Rv3842c 0.71 +0.2
4,315,468 + Rv3842c 0.88 +0.5
4,315,469 - Rv3842c 0.89 +0.3
4,315,481 + +1.6
4,315,481 + +0.3
4,315,481 + +0.2
4,315,481 + +0.6
4,315,569 + +0.0
4,315,570 - +0.8
4,315,570 - -0.2
4,316,003 - Rv3843c 0.42 +2.4
4,316,003 - Rv3843c 0.42 +0.7
4,316,340 - Rv3843c 0.75 +1.0

Or see this region's nucleotide sequence