Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3771c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3770c and Rv3770A are separated by 105 nucleotidesRv3770A and Rv3770B are separated by 14 nucleotidesRv3770B and Rv3771c are separated by 134 nucleotidesRv3771c and GFF3924 are separated by 134 nucleotidesGFF3924 and GFF3925 are separated by 30 nucleotidesGFF3925 and Rv3772 are separated by 77 nucleotides Rv3770c: Rv3770c - Hypothetical leucine rich protein, at 4,215,200 to 4,215,775 Rv3770c Rv3770A: Rv3770A - Probable remnant of a transposase, at 4,215,881 to 4,216,063 Rv3770A Rv3770B: Rv3770B - Probable remnant of a transposase, at 4,216,078 to 4,216,269 Rv3770B Rv3771c: Rv3771c - Conserved hypothetical protein, at 4,216,404 to 4,216,730 Rv3771c GFF3924 - tRNA-Arg, at 4,216,865 to 4,216,937 GFF3924 GFF3925 - tRNA-Ser, at 4,216,968 to 4,217,056 GFF3925 Rv3772: Rv3772 - Probable histidinol-phosphate aminotransferase HisC2 (imidazole acetol-phosphate transaminase) (imidazolylacetolphosphate aminotransferase), at 4,217,134 to 4,218,195 Rv3772 Position (kb) 4216 4217Strain fitness (log2 ratio) -1 0 1 2at 4215.710 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.714 kb on + strand, within Rv3770cat 4215.715 kb on - strand, within Rv3770cat 4215.715 kb on - strand, within Rv3770cat 4215.718 kb on - strandat 4215.746 kb on - strandat 4215.762 kb on - strandat 4215.762 kb on - strandat 4215.770 kb on - strandat 4215.778 kb on + strandat 4215.779 kb on - strandat 4216.079 kb on + strandat 4216.080 kb on - strandat 4216.105 kb on - strand, within Rv3770Bat 4216.105 kb on - strand, within Rv3770Bat 4216.278 kb on - strandat 4216.525 kb on + strand, within Rv3771cat 4216.526 kb on - strand, within Rv3771cat 4216.743 kb on + strandat 4216.743 kb on + strandat 4216.744 kb on - strandat 4216.744 kb on - strandat 4216.744 kb on - strandat 4216.833 kb on + strandat 4216.834 kb on - strandat 4217.123 kb on - strandat 4217.123 kb on - strandat 4217.692 kb on + strand, within Rv3772at 4217.692 kb on + strand, within Rv3772at 4217.693 kb on - strand, within Rv3772at 4217.701 kb on + strand, within Rv3772at 4217.701 kb on + strand, within Rv3772at 4217.702 kb on - strand, within Rv3772at 4217.702 kb on - strand, within Rv3772

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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4,215,710 + Rv3770c 0.89 +1.7
4,215,714 + Rv3770c 0.89 -1.4
4,215,714 + Rv3770c 0.89 +0.4
4,215,714 + Rv3770c 0.89 +1.5
4,215,714 + Rv3770c 0.89 -0.4
4,215,714 + Rv3770c 0.89 -0.9
4,215,714 + Rv3770c 0.89 -0.3
4,215,715 - Rv3770c 0.89 -1.2
4,215,715 - Rv3770c 0.89 -0.3
4,215,718 - -1.0
4,215,746 - -0.0
4,215,762 - +0.3
4,215,762 - -0.5
4,215,770 - -0.1
4,215,778 + +0.3
4,215,779 - -0.0
4,216,079 + +0.0
4,216,080 - -0.0
4,216,105 - Rv3770B 0.14 +0.3
4,216,105 - Rv3770B 0.14 +0.2
4,216,278 - -0.1
4,216,525 + Rv3771c 0.37 +0.5
4,216,526 - Rv3771c 0.37 +0.3
4,216,743 + -0.2
4,216,743 + +0.7
4,216,744 - +0.5
4,216,744 - -0.2
4,216,744 - -0.8
4,216,833 + -0.0
4,216,834 - -0.7
4,217,123 - +1.9
4,217,123 - +0.6
4,217,692 + Rv3772 0.53 -0.2
4,217,692 + Rv3772 0.53 -0.4
4,217,693 - Rv3772 0.53 -0.6
4,217,701 + Rv3772 0.53 -0.3
4,217,701 + Rv3772 0.53 -0.4
4,217,702 - Rv3772 0.53 +0.4
4,217,702 - Rv3772 0.53 +0.0

Or see this region's nucleotide sequence