Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3499c

Experiment: 7H9 with Sulfamethizole 0.026 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3498c and Rv3499c overlap by 1 nucleotidesRv3499c and Rv3500c are separated by 19 nucleotidesRv3500c and Rv3501c are separated by 34 nucleotides Rv3498c: Rv3498c - Mce-family protein Mce4B, at 3,916,946 to 3,917,998 Rv3498c Rv3499c: Rv3499c - Mce-family protein Mce4A, at 3,917,998 to 3,919,200 Rv3499c Rv3500c: Rv3500c - Conserved integral membrane protein YrbE4B. Possible ABC transporter., at 3,919,220 to 3,920,062 Rv3500c Rv3501c: Rv3501c - Conserved integral membrane protein YrbE4A. Possible ABC transporter., at 3,920,097 to 3,920,861 Rv3501c Position (kb) 3917 3918 3919 3920Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3917.055 kb on + strand, within Rv3498cat 3917.103 kb on + strand, within Rv3498cat 3917.103 kb on + strand, within Rv3498cat 3917.103 kb on + strand, within Rv3498cat 3917.391 kb on - strand, within Rv3498cat 3917.715 kb on + strand, within Rv3498cat 3917.716 kb on - strand, within Rv3498cat 3917.724 kb on + strand, within Rv3498cat 3917.725 kb on - strand, within Rv3498cat 3917.865 kb on + strand, within Rv3498cat 3917.866 kb on - strand, within Rv3498cat 3918.086 kb on + strandat 3918.227 kb on + strand, within Rv3499cat 3918.227 kb on + strand, within Rv3499cat 3918.227 kb on + strand, within Rv3499cat 3918.228 kb on - strand, within Rv3499cat 3918.228 kb on - strand, within Rv3499cat 3918.276 kb on + strand, within Rv3499cat 3918.435 kb on - strand, within Rv3499cat 3918.441 kb on + strand, within Rv3499cat 3918.442 kb on - strand, within Rv3499cat 3918.445 kb on - strand, within Rv3499cat 3918.463 kb on + strand, within Rv3499cat 3918.464 kb on - strand, within Rv3499cat 3918.563 kb on + strand, within Rv3499cat 3918.563 kb on + strand, within Rv3499cat 3918.563 kb on + strand, within Rv3499cat 3918.614 kb on - strand, within Rv3499cat 3918.746 kb on - strand, within Rv3499cat 3919.017 kb on - strand, within Rv3499cat 3919.017 kb on - strand, within Rv3499cat 3919.101 kb on + strandat 3919.104 kb on - strandat 3919.255 kb on - strandat 3919.363 kb on - strand, within Rv3500cat 3919.369 kb on - strand, within Rv3500cat 3919.369 kb on - strand, within Rv3500cat 3919.371 kb on + strand, within Rv3500cat 3919.372 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.376 kb on - strand, within Rv3500cat 3919.402 kb on + strand, within Rv3500cat 3919.403 kb on - strand, within Rv3500cat 3919.418 kb on - strand, within Rv3500cat 3919.461 kb on + strand, within Rv3500cat 3919.462 kb on - strand, within Rv3500cat 3919.470 kb on + strand, within Rv3500cat 3919.471 kb on - strand, within Rv3500cat 3919.471 kb on - strand, within Rv3500cat 3919.548 kb on + strand, within Rv3500cat 3919.549 kb on - strand, within Rv3500cat 3919.549 kb on - strand, within Rv3500cat 3919.600 kb on - strand, within Rv3500cat 3919.800 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.956 kb on + strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.957 kb on - strand, within Rv3500cat 3919.974 kb on + strand, within Rv3500cat 3920.055 kb on + strandat 3920.056 kb on - strandat 3920.056 kb on - strandat 3920.121 kb on + strandat 3920.121 kb on + strandat 3920.121 kb on + strandat 3920.122 kb on - strandat 3920.122 kb on - strandat 3920.136 kb on + strandat 3920.136 kb on + strandat 3920.136 kb on + strandat 3920.137 kb on - strandat 3920.137 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
remove
3,917,055 + Rv3498c 0.10 +0.4
3,917,103 + Rv3498c 0.15 -0.1
3,917,103 + Rv3498c 0.15 -0.4
3,917,103 + Rv3498c 0.15 -0.3
3,917,391 - Rv3498c 0.42 -0.1
3,917,715 + Rv3498c 0.73 -1.0
3,917,716 - Rv3498c 0.73 -0.8
3,917,724 + Rv3498c 0.74 -0.7
3,917,725 - Rv3498c 0.74 -0.7
3,917,865 + Rv3498c 0.87 -1.8
3,917,866 - Rv3498c 0.87 -2.0
3,918,086 + -0.4
3,918,227 + Rv3499c 0.19 -1.0
3,918,227 + Rv3499c 0.19 -0.2
3,918,227 + Rv3499c 0.19 -0.3
3,918,228 - Rv3499c 0.19 -0.7
3,918,228 - Rv3499c 0.19 +0.7
3,918,276 + Rv3499c 0.23 -0.5
3,918,435 - Rv3499c 0.36 -0.2
3,918,441 + Rv3499c 0.37 +0.4
3,918,442 - Rv3499c 0.37 -0.4
3,918,445 - Rv3499c 0.37 -1.2
3,918,463 + Rv3499c 0.39 -0.5
3,918,464 - Rv3499c 0.39 -0.8
3,918,563 + Rv3499c 0.47 -0.4
3,918,563 + Rv3499c 0.47 +0.6
3,918,563 + Rv3499c 0.47 -0.8
3,918,614 - Rv3499c 0.51 -1.4
3,918,746 - Rv3499c 0.62 -0.1
3,919,017 - Rv3499c 0.85 -0.5
3,919,017 - Rv3499c 0.85 -0.8
3,919,101 + -0.6
3,919,104 - +0.1
3,919,255 - -0.2
3,919,363 - Rv3500c 0.17 -0.3
3,919,369 - Rv3500c 0.18 -0.8
3,919,369 - Rv3500c 0.18 -0.7
3,919,371 + Rv3500c 0.18 +0.5
3,919,372 - Rv3500c 0.18 -0.4
3,919,376 - Rv3500c 0.19 -0.4
3,919,376 - Rv3500c 0.19 -0.9
3,919,376 - Rv3500c 0.19 -0.6
3,919,402 + Rv3500c 0.22 -0.8
3,919,403 - Rv3500c 0.22 +0.9
3,919,418 - Rv3500c 0.23 -0.9
3,919,461 + Rv3500c 0.29 +1.0
3,919,462 - Rv3500c 0.29 -0.8
3,919,470 + Rv3500c 0.30 +0.7
3,919,471 - Rv3500c 0.30 -0.8
3,919,471 - Rv3500c 0.30 -0.0
3,919,548 + Rv3500c 0.39 -1.1
3,919,549 - Rv3500c 0.39 -1.4
3,919,549 - Rv3500c 0.39 -0.0
3,919,600 - Rv3500c 0.45 -0.5
3,919,800 + Rv3500c 0.69 -0.7
3,919,956 + Rv3500c 0.87 -1.3
3,919,956 + Rv3500c 0.87 -0.0
3,919,956 + Rv3500c 0.87 +0.6
3,919,957 - Rv3500c 0.87 -0.5
3,919,957 - Rv3500c 0.87 -2.8
3,919,957 - Rv3500c 0.87 -0.7
3,919,957 - Rv3500c 0.87 -0.6
3,919,974 + Rv3500c 0.89 +1.9
3,920,055 + -0.1
3,920,056 - -1.0
3,920,056 - +0.9
3,920,121 + +1.3
3,920,121 + -0.6
3,920,121 + +1.1
3,920,122 - +0.3
3,920,122 - +0.1
3,920,136 + -0.5
3,920,136 + -0.6
3,920,136 + -1.0
3,920,137 - -1.3
3,920,137 - -0.1

Or see this region's nucleotide sequence