Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2736c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2735c and Rv2736c are separated by 9 nucleotidesRv2736c and Rv2737c overlap by 35 nucleotides Rv2734: Rv2734 - Conserved hypothetical protein, at 3,046,821 to 3,047,675 Rv2734 Rv2735c: Rv2735c - Conserved hypothetical protein, at 3,047,560 to 3,048,552 Rv2735c Rv2736c: Rv2736c - Regulatory protein RecX, at 3,048,562 to 3,049,086 Rv2736c Rv2737c: Rv2737c - RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]., at 3,049,052 to 3,051,424 Rv2737c Position (kb) 3048 3049 3050Strain fitness (log2 ratio) -2 -1 0 1at 3047.677 kb on + strand, within Rv2735cat 3047.771 kb on + strand, within Rv2735cat 3047.772 kb on - strand, within Rv2735cat 3047.841 kb on + strand, within Rv2735cat 3047.842 kb on - strand, within Rv2735cat 3047.842 kb on - strand, within Rv2735cat 3047.862 kb on + strand, within Rv2735cat 3047.873 kb on + strand, within Rv2735cat 3047.874 kb on - strand, within Rv2735cat 3047.874 kb on - strand, within Rv2735cat 3047.916 kb on + strand, within Rv2735cat 3047.916 kb on + strand, within Rv2735cat 3047.916 kb on + strand, within Rv2735cat 3047.933 kb on + strand, within Rv2735cat 3047.947 kb on + strand, within Rv2735cat 3047.947 kb on + strand, within Rv2735cat 3047.948 kb on - strand, within Rv2735cat 3047.948 kb on - strand, within Rv2735cat 3047.975 kb on - strand, within Rv2735cat 3047.999 kb on + strand, within Rv2735cat 3047.999 kb on + strand, within Rv2735cat 3047.999 kb on + strand, within Rv2735cat 3047.999 kb on + strand, within Rv2735cat 3048.000 kb on - strand, within Rv2735cat 3048.000 kb on - strand, within Rv2735cat 3048.086 kb on - strand, within Rv2735cat 3048.208 kb on + strand, within Rv2735cat 3048.208 kb on + strand, within Rv2735cat 3048.497 kb on + strandat 3048.508 kb on + strandat 3048.547 kb on - strandat 3048.728 kb on - strand, within Rv2736cat 3049.550 kb on + strand, within Rv2737cat 3049.551 kb on - strand, within Rv2737cat 3049.551 kb on - strand, within Rv2737cat 3049.551 kb on - strand, within Rv2737cat 3049.678 kb on - strand, within Rv2737cat 3049.678 kb on - strand, within Rv2737cat 3049.678 kb on - strand, within Rv2737cat 3049.678 kb on - strand, within Rv2737c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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3,047,677 + Rv2735c 0.12 -0.8
3,047,771 + Rv2735c 0.21 -0.4
3,047,772 - Rv2735c 0.21 -0.5
3,047,841 + Rv2735c 0.28 -0.7
3,047,842 - Rv2735c 0.28 +1.3
3,047,842 - Rv2735c 0.28 -0.3
3,047,862 + Rv2735c 0.30 -0.7
3,047,873 + Rv2735c 0.32 -1.8
3,047,874 - Rv2735c 0.32 -0.0
3,047,874 - Rv2735c 0.32 +0.2
3,047,916 + Rv2735c 0.36 -0.1
3,047,916 + Rv2735c 0.36 +0.5
3,047,916 + Rv2735c 0.36 -0.4
3,047,933 + Rv2735c 0.38 -1.4
3,047,947 + Rv2735c 0.39 +0.4
3,047,947 + Rv2735c 0.39 -0.4
3,047,948 - Rv2735c 0.39 +0.4
3,047,948 - Rv2735c 0.39 -1.0
3,047,975 - Rv2735c 0.42 -0.0
3,047,999 + Rv2735c 0.44 -0.3
3,047,999 + Rv2735c 0.44 +1.2
3,047,999 + Rv2735c 0.44 -0.1
3,047,999 + Rv2735c 0.44 +0.0
3,048,000 - Rv2735c 0.44 -0.4
3,048,000 - Rv2735c 0.44 +0.2
3,048,086 - Rv2735c 0.53 +0.2
3,048,208 + Rv2735c 0.65 -1.5
3,048,208 + Rv2735c 0.65 +0.3
3,048,497 + -0.1
3,048,508 + +0.2
3,048,547 - +0.7
3,048,728 - Rv2736c 0.32 +0.5
3,049,550 + Rv2737c 0.21 +0.6
3,049,551 - Rv2737c 0.21 -0.9
3,049,551 - Rv2737c 0.21 +0.1
3,049,551 - Rv2737c 0.21 +0.7
3,049,678 - Rv2737c 0.26 -0.4
3,049,678 - Rv2737c 0.26 -0.5
3,049,678 - Rv2737c 0.26 -0.2
3,049,678 - Rv2737c 0.26 -0.6

Or see this region's nucleotide sequence