Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2633c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2631 and Rv2632c are separated by 38 nucleotidesRv2632c and Rv2633c are separated by 144 nucleotidesRv2633c and Rv2634c are separated by 284 nucleotides Rv2631: Rv2631 - Conserved hypothetical protein, at 2,957,572 to 2,958,870 Rv2631 Rv2632c: Rv2632c - Conserved protein, at 2,958,909 to 2,959,190 Rv2632c Rv2633c: Rv2633c - Hypothetical protein, at 2,959,335 to 2,959,820 Rv2633c Rv2634c: Rv2634c - PE-PGRS family protein PE_PGRS46, at 2,960,105 to 2,962,441 Rv2634c Position (kb) 2959 2960Strain fitness (log2 ratio) -2 -1 0 1 2at 2958.586 kb on + strand, within Rv2631at 2958.587 kb on - strand, within Rv2631at 2958.587 kb on - strand, within Rv2631at 2958.587 kb on - strand, within Rv2631at 2958.650 kb on + strand, within Rv2631at 2958.650 kb on + strand, within Rv2631at 2958.745 kb on - strandat 2958.942 kb on - strand, within Rv2632cat 2958.975 kb on + strand, within Rv2632cat 2959.218 kb on - strandat 2959.239 kb on + strandat 2959.252 kb on + strandat 2959.256 kb on + strandat 2959.256 kb on + strandat 2959.256 kb on + strandat 2959.256 kb on + strandat 2959.257 kb on - strandat 2959.284 kb on + strandat 2959.336 kb on + strandat 2959.336 kb on + strandat 2959.337 kb on - strandat 2959.371 kb on - strandat 2959.382 kb on - strandat 2959.382 kb on - strandat 2959.382 kb on - strandat 2959.382 kb on - strandat 2959.382 kb on - strandat 2959.497 kb on + strand, within Rv2633cat 2959.498 kb on - strand, within Rv2633cat 2959.661 kb on - strand, within Rv2633cat 2959.663 kb on + strand, within Rv2633cat 2959.663 kb on + strand, within Rv2633cat 2959.663 kb on + strand, within Rv2633cat 2959.664 kb on - strand, within Rv2633cat 2959.664 kb on - strand, within Rv2633cat 2959.778 kb on + strandat 2959.800 kb on + strandat 2959.804 kb on - strandat 2959.831 kb on + strandat 2959.862 kb on + strandat 2960.107 kb on - strandat 2960.470 kb on + strand, within Rv2634cat 2960.804 kb on + strand, within Rv2634c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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2,958,586 + Rv2631 0.78 -0.4
2,958,587 - Rv2631 0.78 +0.3
2,958,587 - Rv2631 0.78 -0.0
2,958,587 - Rv2631 0.78 +0.8
2,958,650 + Rv2631 0.83 +0.7
2,958,650 + Rv2631 0.83 +0.3
2,958,745 - +0.1
2,958,942 - Rv2632c 0.12 +0.1
2,958,975 + Rv2632c 0.23 -0.2
2,959,218 - -0.1
2,959,239 + -0.2
2,959,252 + +1.3
2,959,256 + +0.8
2,959,256 + -0.2
2,959,256 + -0.6
2,959,256 + -0.2
2,959,257 - +0.3
2,959,284 + +0.2
2,959,336 + -0.4
2,959,336 + +1.8
2,959,337 - +1.8
2,959,371 - +2.4
2,959,382 - +0.3
2,959,382 - +0.7
2,959,382 - +0.4
2,959,382 - +0.4
2,959,382 - +0.8
2,959,497 + Rv2633c 0.33 +0.3
2,959,498 - Rv2633c 0.34 +0.6
2,959,661 - Rv2633c 0.67 +0.2
2,959,663 + Rv2633c 0.67 +0.7
2,959,663 + Rv2633c 0.67 +0.8
2,959,663 + Rv2633c 0.67 -0.3
2,959,664 - Rv2633c 0.68 +0.8
2,959,664 - Rv2633c 0.68 +0.5
2,959,778 + +0.3
2,959,800 + +0.9
2,959,804 - +0.9
2,959,831 + -1.4
2,959,862 + +1.4
2,960,107 - -2.0
2,960,470 + Rv2634c 0.16 -0.9
2,960,804 + Rv2634c 0.30 -0.1

Or see this region's nucleotide sequence