Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1426c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1425 and Rv1426c are separated by 21 nucleotidesRv1426c and Rv1427c overlap by 1 nucleotides Rv1425: Rv1425 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 1,599,658 to 1,601,037 Rv1425 Rv1426c: Rv1426c - Probable esterase LipO, at 1,601,059 to 1,602,321 Rv1426c Rv1427c: Rv1427c - Possible long-chain-fatty-acid--CoA ligase FadD12 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,602,321 to 1,603,928 Rv1427c Position (kb) 1601 1602 1603Strain fitness (log2 ratio) -2 -1 0 1 2at 1600.481 kb on - strand, within Rv1425at 1600.481 kb on - strand, within Rv1425at 1600.612 kb on - strand, within Rv1425at 1600.757 kb on - strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.840 kb on - strand, within Rv1425at 1600.930 kb on + strandat 1601.035 kb on + strandat 1601.041 kb on + strandat 1601.041 kb on + strandat 1601.041 kb on + strandat 1601.051 kb on - strandat 1601.052 kb on + strandat 1601.053 kb on - strandat 1601.060 kb on + strandat 1601.084 kb on + strandat 1601.672 kb on + strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.934 kb on + strand, within Rv1426cat 1601.970 kb on + strand, within Rv1426cat 1601.975 kb on + strand, within Rv1426cat 1602.164 kb on + strand, within Rv1426cat 1602.165 kb on - strand, within Rv1426cat 1602.418 kb on + strandat 1602.418 kb on + strandat 1602.418 kb on + strandat 1602.514 kb on + strand, within Rv1427cat 1602.595 kb on + strand, within Rv1427cat 1602.595 kb on + strand, within Rv1427cat 1602.728 kb on + strand, within Rv1427cat 1602.729 kb on - strand, within Rv1427cat 1602.729 kb on - strand, within Rv1427cat 1602.731 kb on - strand, within Rv1427cat 1602.760 kb on + strand, within Rv1427c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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1,600,481 - Rv1425 0.60 -0.1
1,600,481 - Rv1425 0.60 +0.8
1,600,612 - Rv1425 0.69 +0.2
1,600,757 - Rv1425 0.80 -0.1
1,600,837 + Rv1425 0.85 -0.2
1,600,837 + Rv1425 0.85 -0.3
1,600,837 + Rv1425 0.85 -1.8
1,600,837 + Rv1425 0.85 -0.8
1,600,838 - Rv1425 0.86 +0.2
1,600,838 - Rv1425 0.86 -0.8
1,600,838 - Rv1425 0.86 +0.5
1,600,838 - Rv1425 0.86 -0.0
1,600,839 + Rv1425 0.86 -0.5
1,600,839 + Rv1425 0.86 +0.1
1,600,839 + Rv1425 0.86 -0.2
1,600,840 - Rv1425 0.86 -0.5
1,600,930 + +1.8
1,601,035 + -0.9
1,601,041 + -0.4
1,601,041 + -0.3
1,601,041 + +0.7
1,601,051 - +0.4
1,601,052 + +0.3
1,601,053 - -0.4
1,601,060 + +0.3
1,601,084 + +0.8
1,601,672 + Rv1426c 0.49 -0.8
1,601,673 - Rv1426c 0.49 -0.4
1,601,673 - Rv1426c 0.49 -0.0
1,601,858 + Rv1426c 0.63 -0.5
1,601,858 + Rv1426c 0.63 +0.6
1,601,934 + Rv1426c 0.69 -0.2
1,601,970 + Rv1426c 0.72 -0.1
1,601,975 + Rv1426c 0.73 -0.3
1,602,164 + Rv1426c 0.87 -0.9
1,602,165 - Rv1426c 0.88 -0.5
1,602,418 + +0.2
1,602,418 + -0.1
1,602,418 + -0.2
1,602,514 + Rv1427c 0.12 -0.1
1,602,595 + Rv1427c 0.17 -0.8
1,602,595 + Rv1427c 0.17 -0.0
1,602,728 + Rv1427c 0.25 -0.9
1,602,729 - Rv1427c 0.25 -0.3
1,602,729 - Rv1427c 0.25 -0.4
1,602,731 - Rv1427c 0.25 -0.5
1,602,760 + Rv1427c 0.27 -1.8

Or see this region's nucleotide sequence