Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1035c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1033c and Rv1034c are separated by 181 nucleotidesRv1034c and Rv1035c are separated by 67 nucleotidesRv1035c and Rv1036c are separated by 33 nucleotidesRv1036c and Rv1037c are separated by 110 nucleotidesRv1037c and Rv1038c are separated by 26 nucleotides Rv1033c: Rv1033c - Two component transcriptional regulator TrcR, at 1,157,963 to 1,158,736 Rv1033c Rv1034c: Rv1034c - Probable transposase (fragment), at 1,158,918 to 1,159,307 Rv1034c Rv1035c: Rv1035c - Probable transposase (fragment), at 1,159,375 to 1,160,061 Rv1035c Rv1036c: Rv1036c - Probable IS1560 transposase (fragment), at 1,160,095 to 1,160,433 Rv1036c Rv1037c: Rv1037c - Putative ESAT-6 like protein EsxI (ESAT-6 like protein 1), at 1,160,544 to 1,160,828 Rv1037c Rv1038c: Rv1038c - ESAT-6 like protein EsxJ (ESAT-6 like protein 2), at 1,160,855 to 1,161,151 Rv1038c Position (kb) 1159 1160 1161Strain fitness (log2 ratio) -1 0 1at 1158.429 kb on + strand, within Rv1033cat 1158.579 kb on + strand, within Rv1033cat 1158.580 kb on - strand, within Rv1033cat 1158.718 kb on - strandat 1158.745 kb on - strandat 1158.745 kb on - strandat 1158.813 kb on + strandat 1158.896 kb on + strandat 1159.516 kb on + strand, within Rv1035cat 1159.902 kb on - strand, within Rv1035cat 1160.177 kb on + strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.345 kb on - strand, within Rv1036cat 1160.446 kb on - strandat 1160.446 kb on - strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.459 kb on - strandat 1160.463 kb on - strandat 1160.463 kb on - strandat 1160.516 kb on - strandat 1160.534 kb on + strandat 1160.534 kb on + strandat 1160.534 kb on + strandat 1160.535 kb on - strandat 1160.546 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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1,158,429 + Rv1033c 0.60 -0.2
1,158,579 + Rv1033c 0.80 -0.6
1,158,580 - Rv1033c 0.80 +1.0
1,158,718 - -0.4
1,158,745 - -0.4
1,158,745 - -0.4
1,158,813 + -0.0
1,158,896 + -0.2
1,159,516 + Rv1035c 0.21 -0.1
1,159,902 - Rv1035c 0.77 +1.2
1,160,177 + Rv1036c 0.24 +1.4
1,160,178 - Rv1036c 0.24 +0.2
1,160,178 - Rv1036c 0.24 -0.3
1,160,178 - Rv1036c 0.24 +0.1
1,160,178 - Rv1036c 0.24 -0.2
1,160,345 - Rv1036c 0.74 -0.2
1,160,446 - +0.0
1,160,446 - -1.1
1,160,458 + +0.1
1,160,458 + +0.9
1,160,458 + +0.2
1,160,458 + +0.0
1,160,459 - -0.2
1,160,463 - +0.0
1,160,463 - +0.4
1,160,516 - +0.3
1,160,534 + -0.2
1,160,534 + +0.2
1,160,534 + -0.2
1,160,535 - -1.2
1,160,546 - -0.0

Or see this region's nucleotide sequence