Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0580c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0579 and Rv0580c are separated by 128 nucleotidesRv0580c and Rv0581 are separated by 93 nucleotidesRv0581 and Rv0582 overlap by 4 nucleotidesRv0582 and Rv0583c are separated by 59 nucleotides Rv0579: Rv0579 - Conserved hypothetical protein, at 676,238 to 676,996 Rv0579 Rv0580c: Rv0580c - Conserved protein, at 677,125 to 677,616 Rv0580c Rv0581: Rv0581 - Possible antitoxin VapB26, at 677,710 to 677,925 Rv0581 Rv0582: Rv0582 - Possible toxin VapC26. Contains PIN domain., at 677,922 to 678,329 Rv0582 Rv0583c: Rv0583c - Probable conserved lipoprotein LpqN, at 678,389 to 679,075 Rv0583c Position (kb) 677 678Strain fitness (log2 ratio) -1 0 1 2 3at 676.144 kb on + strandat 676.145 kb on - strandat 676.145 kb on - strandat 676.159 kb on - strandat 676.232 kb on + strandat 676.233 kb on - strandat 676.247 kb on + strandat 676.379 kb on - strand, within Rv0579at 676.460 kb on + strand, within Rv0579at 676.465 kb on + strand, within Rv0579at 676.466 kb on - strand, within Rv0579at 676.523 kb on - strand, within Rv0579at 676.523 kb on - strand, within Rv0579at 676.984 kb on + strandat 677.261 kb on + strand, within Rv0580cat 677.627 kb on + strandat 677.680 kb on - strandat 677.859 kb on - strand, within Rv0581at 677.859 kb on - strand, within Rv0581at 677.861 kb on - strand, within Rv0581at 678.555 kb on + strand, within Rv0583cat 678.555 kb on + strand, within Rv0583c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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676,144 + -0.3
676,145 - +2.8
676,145 - +0.2
676,159 - +1.0
676,232 + +0.4
676,233 - -0.1
676,247 + -0.8
676,379 - Rv0579 0.19 -0.6
676,460 + Rv0579 0.29 -0.5
676,465 + Rv0579 0.30 -0.2
676,466 - Rv0579 0.30 -0.7
676,523 - Rv0579 0.38 +0.2
676,523 - Rv0579 0.38 +0.0
676,984 + +0.7
677,261 + Rv0580c 0.28 +0.3
677,627 + -0.1
677,680 - -0.3
677,859 - Rv0581 0.69 -0.1
677,859 - Rv0581 0.69 -0.5
677,861 - Rv0581 0.70 +1.3
678,555 + Rv0583c 0.24 +0.6
678,555 + Rv0583c 0.24 -0.3

Or see this region's nucleotide sequence