Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3577

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3576 and Rv3577 are separated by 190 nucleotidesRv3577 and Rv3578 are separated by 13 nucleotides Rv3576: Rv3576 - Possible conserved lipoprotein LppH, at 4,018,358 to 4,019,071 Rv3576 Rv3577: Rv3577 - Conserved hypothetical protein, at 4,019,262 to 4,020,128 Rv3577 Rv3578: Rv3578 - Possible arsenical pump integral membrane protein ArsB2, at 4,020,142 to 4,021,383 Rv3578 Position (kb) 4019 4020 4021Strain fitness (log2 ratio) -2 -1 0 1at 4018.322 kb on + strandat 4018.322 kb on + strandat 4018.323 kb on - strandat 4018.787 kb on + strand, within Rv3576at 4018.788 kb on - strand, within Rv3576at 4018.909 kb on + strand, within Rv3576at 4018.982 kb on - strand, within Rv3576at 4019.006 kb on - strandat 4019.117 kb on + strandat 4019.117 kb on + strandat 4019.258 kb on + strandat 4019.863 kb on - strand, within Rv3577at 4019.901 kb on + strand, within Rv3577at 4019.902 kb on - strand, within Rv3577at 4019.902 kb on - strand, within Rv3577at 4019.902 kb on - strand, within Rv3577at 4020.032 kb on - strand, within Rv3577at 4020.032 kb on - strand, within Rv3577at 4020.136 kb on + strandat 4020.556 kb on + strand, within Rv3578at 4020.557 kb on - strand, within Rv3578at 4020.628 kb on + strand, within Rv3578at 4020.628 kb on + strand, within Rv3578at 4020.706 kb on + strand, within Rv3578at 4020.706 kb on + strand, within Rv3578at 4020.707 kb on - strand, within Rv3578at 4020.740 kb on + strand, within Rv3578

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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4,018,322 + -1.3
4,018,322 + +0.2
4,018,323 - -1.0
4,018,787 + Rv3576 0.60 -0.5
4,018,788 - Rv3576 0.60 -0.8
4,018,909 + Rv3576 0.77 -0.1
4,018,982 - Rv3576 0.87 +0.0
4,019,006 - +0.6
4,019,117 + -0.7
4,019,117 + -0.4
4,019,258 + -0.1
4,019,863 - Rv3577 0.69 -0.9
4,019,901 + Rv3577 0.74 +0.4
4,019,902 - Rv3577 0.74 -0.9
4,019,902 - Rv3577 0.74 +0.5
4,019,902 - Rv3577 0.74 -0.1
4,020,032 - Rv3577 0.89 -0.9
4,020,032 - Rv3577 0.89 -0.2
4,020,136 + -1.5
4,020,556 + Rv3578 0.33 -0.3
4,020,557 - Rv3578 0.33 -0.1
4,020,628 + Rv3578 0.39 -0.5
4,020,628 + Rv3578 0.39 -0.2
4,020,706 + Rv3578 0.45 +0.2
4,020,706 + Rv3578 0.45 +0.1
4,020,707 - Rv3578 0.45 -0.3
4,020,740 + Rv3578 0.48 -1.8

Or see this region's nucleotide sequence