Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2039c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2038c and Rv2039c are separated by 2 nucleotidesRv2039c and Rv2040c overlap by 14 nucleotidesRv2040c and Rv2041c overlap by 4 nucleotides Rv2038c: Rv2038c - Probable sugar-transport ATP-binding protein ABC transporter, at 2,283,723 to 2,284,796 Rv2038c Rv2039c: Rv2039c - Probable sugar-transport integral membrane protein ABC transporter, at 2,284,799 to 2,285,641 Rv2039c Rv2040c: Rv2040c - Probable sugar-transport integral membrane protein ABC transporter, at 2,285,628 to 2,286,530 Rv2040c Rv2041c: Rv2041c - Probable sugar-binding lipoprotein, at 2,286,527 to 2,287,846 Rv2041c Position (kb) 2284 2285 2286Strain fitness (log2 ratio) -1 0 1 2at 2283.880 kb on + strand, within Rv2038cat 2283.886 kb on + strand, within Rv2038cat 2284.225 kb on + strand, within Rv2038cat 2284.653 kb on + strand, within Rv2038cat 2284.858 kb on - strandat 2284.923 kb on + strand, within Rv2039cat 2284.924 kb on - strand, within Rv2039cat 2285.083 kb on - strand, within Rv2039cat 2285.171 kb on - strand, within Rv2039cat 2285.791 kb on + strand, within Rv2040cat 2285.796 kb on - strand, within Rv2040cat 2285.871 kb on + strand, within Rv2040cat 2285.969 kb on - strand, within Rv2040cat 2286.424 kb on + strand, within Rv2040cat 2286.425 kb on - strand, within Rv2040cat 2286.491 kb on + strandat 2286.491 kb on + strandat 2286.492 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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2,283,880 + Rv2038c 0.15 -1.7
2,283,886 + Rv2038c 0.15 +0.6
2,284,225 + Rv2038c 0.47 -0.5
2,284,653 + Rv2038c 0.87 -0.3
2,284,858 - +0.8
2,284,923 + Rv2039c 0.15 -0.4
2,284,924 - Rv2039c 0.15 +1.2
2,285,083 - Rv2039c 0.34 -0.6
2,285,171 - Rv2039c 0.44 +0.2
2,285,791 + Rv2040c 0.18 +1.5
2,285,796 - Rv2040c 0.19 +0.8
2,285,871 + Rv2040c 0.27 -1.4
2,285,969 - Rv2040c 0.38 +0.1
2,286,424 + Rv2040c 0.88 +0.4
2,286,425 - Rv2040c 0.88 +1.4
2,286,491 + -1.7
2,286,491 + +1.8
2,286,492 - -0.0

Or see this region's nucleotide sequence