Experiment: 7H9 with Sulfamethizole 0.026 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1552 and Rv1553 are separated by 2 nucleotides Rv1553 and Rv1554 overlap by 4 nucleotides Rv1554 and Rv1555 overlap by 4 nucleotides Rv1555 and Rv1556 are separated by 67 nucleotides
Rv1552: Rv1552 - Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase), at 1,757,681 to 1,759,432
Rv1552
Rv1553: Rv1553 - Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase), at 1,759,435 to 1,760,178
Rv1553
Rv1554: Rv1554 - Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogenase) (fumaric hydrogenase), at 1,760,175 to 1,760,555
Rv1554
Rv1555: Rv1555 - Probable fumarate reductase [membrane anchor subunit] FrdD (fumarate dehydrogenase) (fumaric hydrogenase), at 1,760,552 to 1,760,929
Rv1555
Rv1556: Rv1556 - Possible regulatory protein, at 1,760,997 to 1,761,605
Rv1556
Position (kb)
1760
1761 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1759.422 kb on - strand at 1759.422 kb on - strand at 1759.430 kb on + strand at 1759.430 kb on + strand at 1759.430 kb on + strand at 1759.431 kb on - strand at 1759.431 kb on - strand at 1759.431 kb on - strand at 1759.555 kb on + strand, within Rv1553 at 1759.555 kb on + strand, within Rv1553 at 1759.555 kb on + strand, within Rv1553 at 1759.555 kb on + strand, within Rv1553 at 1759.611 kb on + strand, within Rv1553 at 1759.629 kb on + strand, within Rv1553 at 1759.630 kb on - strand, within Rv1553 at 1759.681 kb on + strand, within Rv1553 at 1759.682 kb on - strand, within Rv1553 at 1759.686 kb on - strand, within Rv1553 at 1759.686 kb on - strand, within Rv1553 at 1759.882 kb on - strand, within Rv1553 at 1759.882 kb on - strand, within Rv1553 at 1759.973 kb on - strand, within Rv1553 at 1760.116 kb on + strand at 1760.229 kb on + strand, within Rv1554 at 1760.229 kb on + strand, within Rv1554 at 1760.229 kb on + strand, within Rv1554 at 1760.287 kb on - strand, within Rv1554 at 1760.300 kb on - strand, within Rv1554 at 1760.371 kb on + strand, within Rv1554 at 1760.372 kb on - strand, within Rv1554 at 1760.418 kb on - strand, within Rv1554 at 1760.923 kb on + strand at 1760.923 kb on + strand at 1760.924 kb on - strand at 1760.927 kb on + strand at 1760.927 kb on + strand at 1760.928 kb on - strand at 1760.996 kb on + strand at 1760.997 kb on - strand at 1761.001 kb on + strand at 1761.085 kb on + strand, within Rv1556 at 1761.085 kb on + strand, within Rv1556 at 1761.086 kb on - strand, within Rv1556 at 1761.118 kb on + strand, within Rv1556 at 1761.418 kb on - strand, within Rv1556
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM remove 1,759,422 - -0.7 1,759,422 - -0.3 1,759,430 + -0.2 1,759,430 + +0.8 1,759,430 + -0.1 1,759,431 - -0.0 1,759,431 - -0.2 1,759,431 - -2.0 1,759,555 + Rv1553 0.16 -0.3 1,759,555 + Rv1553 0.16 -1.2 1,759,555 + Rv1553 0.16 +1.8 1,759,555 + Rv1553 0.16 -0.1 1,759,611 + Rv1553 0.24 +0.0 1,759,629 + Rv1553 0.26 +0.1 1,759,630 - Rv1553 0.26 +0.1 1,759,681 + Rv1553 0.33 +0.7 1,759,682 - Rv1553 0.33 +0.1 1,759,686 - Rv1553 0.34 -0.2 1,759,686 - Rv1553 0.34 -0.1 1,759,882 - Rv1553 0.60 +0.4 1,759,882 - Rv1553 0.60 -0.6 1,759,973 - Rv1553 0.72 -0.2 1,760,116 + +0.2 1,760,229 + Rv1554 0.14 +0.2 1,760,229 + Rv1554 0.14 -0.7 1,760,229 + Rv1554 0.14 -0.2 1,760,287 - Rv1554 0.29 -0.2 1,760,300 - Rv1554 0.33 -0.2 1,760,371 + Rv1554 0.51 -0.3 1,760,372 - Rv1554 0.52 -1.0 1,760,418 - Rv1554 0.64 -0.3 1,760,923 + +0.3 1,760,923 + -0.1 1,760,924 - +0.3 1,760,927 + -0.8 1,760,927 + -0.2 1,760,928 - -0.4 1,760,996 + -1.3 1,760,997 - -1.1 1,761,001 + -0.3 1,761,085 + Rv1556 0.14 +0.1 1,761,085 + Rv1556 0.14 -0.0 1,761,086 - Rv1556 0.15 -2.0 1,761,118 + Rv1556 0.20 -0.4 1,761,418 - Rv1556 0.69 -0.2
Or see this region's nucleotide sequence