Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1507c

Experiment: 7H9 with Sulfamethizole 0.026 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1505c and Rv1506c overlap by 4 nucleotidesRv1506c and Rv1507c are separated by 283 nucleotidesRv1507c and Rv1507A overlap by 67 nucleotidesRv1507A and Rv1508c are separated by 235 nucleotides Rv1505c: Rv1505c - Conserved hypothetical protein, at 1,695,281 to 1,695,946 Rv1505c Rv1506c: Rv1506c - Hypothetical protein, at 1,695,943 to 1,696,443 Rv1506c Rv1507c: Rv1507c - Conserved protein, at 1,696,727 to 1,697,422 Rv1507c Rv1507A: Rv1507A - Hypothetical protein, at 1,697,356 to 1,697,859 Rv1507A Rv1508c: Rv1508c - Probable membrane protein, at 1,698,095 to 1,699,894 Rv1508c Position (kb) 1696 1697 1698Strain fitness (log2 ratio) -1 0 1at 1696.371 kb on - strand, within Rv1506cat 1696.371 kb on - strand, within Rv1506cat 1696.529 kb on - strandat 1696.626 kb on + strandat 1696.626 kb on + strandat 1696.627 kb on - strandat 1696.718 kb on + strandat 1696.719 kb on - strandat 1696.741 kb on - strandat 1696.829 kb on - strand, within Rv1507cat 1697.259 kb on - strand, within Rv1507cat 1697.607 kb on + strand, within Rv1507Aat 1697.608 kb on - strand, within Rv1507Aat 1697.742 kb on - strand, within Rv1507Aat 1697.742 kb on - strand, within Rv1507Aat 1697.818 kb on - strandat 1697.850 kb on - strandat 1698.008 kb on - strandat 1698.008 kb on - strandat 1698.030 kb on + strandat 1698.096 kb on + strandat 1698.105 kb on + strandat 1698.106 kb on - strandat 1698.208 kb on + strandat 1698.267 kb on - strandat 1698.267 kb on - strandat 1698.267 kb on - strandat 1698.269 kb on + strandat 1698.270 kb on - strandat 1698.338 kb on + strand, within Rv1508cat 1698.364 kb on - strand, within Rv1508cat 1698.376 kb on - strand, within Rv1508c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM
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1,696,371 - Rv1506c 0.85 +0.6
1,696,371 - Rv1506c 0.85 -0.1
1,696,529 - +0.1
1,696,626 + +0.8
1,696,626 + -0.8
1,696,627 - -0.0
1,696,718 + +0.2
1,696,719 - +0.1
1,696,741 - -1.1
1,696,829 - Rv1507c 0.15 -0.1
1,697,259 - Rv1507c 0.76 -0.2
1,697,607 + Rv1507A 0.50 -0.3
1,697,608 - Rv1507A 0.50 +0.9
1,697,742 - Rv1507A 0.77 -0.1
1,697,742 - Rv1507A 0.77 +0.2
1,697,818 - -0.3
1,697,850 - -0.4
1,698,008 - -0.9
1,698,008 - -0.1
1,698,030 + -0.1
1,698,096 + +0.3
1,698,105 + -0.4
1,698,106 - -0.8
1,698,208 + -0.1
1,698,267 - +0.3
1,698,267 - -0.1
1,698,267 - -1.1
1,698,269 + -0.1
1,698,270 - -0.3
1,698,338 + Rv1508c 0.14 -0.2
1,698,364 - Rv1508c 0.15 +0.6
1,698,376 - Rv1508c 0.16 +0.3

Or see this region's nucleotide sequence