Experiment: 7H9 with Sulfamethizole 0.026 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0391 and Rv0392c overlap by 4 nucleotides Rv0392c and Rv0393 are separated by 141 nucleotides
Rv0391: Rv0391 - Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase), at 470,010 to 471,230
Rv0391
Rv0392c: Rv0392c - Probable membrane NADH dehydrogenase NdhA, at 471,227 to 472,639
Rv0392c
Rv0393: Rv0393 - Conserved 13E12 repeat family protein, at 472,781 to 474,106
Rv0393
Position (kb) 471
472
473 Strain fitness (log2 ratio) -3
-2
-1
0
1 at 470.721 kb on + strand, within Rv0391 at 470.929 kb on - strand, within Rv0391 at 471.228 kb on + strand at 471.325 kb on - strand at 472.037 kb on - strand, within Rv0392c at 472.474 kb on - strand, within Rv0392c at 472.541 kb on - strand at 472.673 kb on + strand at 472.674 kb on - strand at 472.674 kb on - strand at 472.681 kb on - strand at 472.706 kb on - strand at 472.854 kb on + strand at 472.854 kb on + strand at 472.855 kb on - strand at 472.855 kb on - strand at 472.894 kb on - strand at 472.992 kb on + strand, within Rv0393 at 473.103 kb on + strand, within Rv0393 at 473.104 kb on - strand, within Rv0393 at 473.213 kb on + strand, within Rv0393 at 473.214 kb on - strand, within Rv0393 at 473.214 kb on - strand, within Rv0393 at 473.225 kb on + strand, within Rv0393 at 473.225 kb on + strand, within Rv0393 at 473.225 kb on + strand, within Rv0393 at 473.226 kb on - strand, within Rv0393
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Sulfamethizole 0.026 mM remove 470,721 + Rv0391 0.58 -1.1 470,929 - Rv0391 0.75 +0.8 471,228 + -0.3 471,325 - -0.8 472,037 - Rv0392c 0.57 -2.8 472,474 - Rv0392c 0.88 -1.3 472,541 - -1.2 472,673 + -0.4 472,674 - +0.1 472,674 - +0.0 472,681 - +0.4 472,706 - -0.9 472,854 + -0.2 472,854 + -0.7 472,855 - +0.0 472,855 - -0.1 472,894 - +0.3 472,992 + Rv0393 0.16 -0.4 473,103 + Rv0393 0.24 -0.1 473,104 - Rv0393 0.24 -0.2 473,213 + Rv0393 0.33 +0.0 473,214 - Rv0393 0.33 +0.1 473,214 - Rv0393 0.33 -1.3 473,225 + Rv0393 0.33 -1.0 473,225 + Rv0393 0.33 +0.1 473,225 + Rv0393 0.33 +0.7 473,226 - Rv0393 0.34 +0.0
Or see this region's nucleotide sequence