Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3621c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
4,059,712	+		Rv3618	0.85	-1.7
4,059,712	+		Rv3618	0.85	-0.6
4,059,713	-		Rv3618	0.85	-0.2
4,059,713	-		Rv3618	0.85	+4.0
4,059,742	+		Rv3618	0.88	-0.1
4,059,790	-				-0.3
4,059,923	-				+0.3
4,059,923	-				-0.1
4,059,973	+				-0.4
4,059,974	-				+0.6
4,059,974	-				-0.3
4,060,591	+				-0.5
4,060,641	+				-0.2
4,060,641	+				+0.4
4,060,642	-				-0.3
4,060,716	+				+2.5
4,061,031	-		Rv3621c	0.31	+0.8
4,061,031	-		Rv3621c	0.31	-0.2
4,061,427	-		Rv3621c	0.63	+0.3
4,061,432	+		Rv3621c	0.63	-0.5
4,061,432	+		Rv3621c	0.63	-0.6
4,061,432	+		Rv3621c	0.63	+0.5
4,061,433	-		Rv3621c	0.63	+0.9
4,061,433	-		Rv3621c	0.63	+0.1
4,061,433	-		Rv3621c	0.63	-0.1
4,061,433	-		Rv3621c	0.63	+2.3
4,061,433	-		Rv3621c	0.63	+0.2
4,061,433	-		Rv3621c	0.63	+0.2
4,061,597	+		Rv3621c	0.76	+0.9
4,061,597	+		Rv3621c	0.76	+0.1
4,061,597	+		Rv3621c	0.76	+0.3
4,061,597	+		Rv3621c	0.76	-0.1
4,061,598	-		Rv3621c	0.76	-0.2
4,061,753	+		Rv3621c	0.89	+0.4
4,061,754	-		Rv3621c	0.89	+1.3
4,061,840	+				+0.1
4,061,840	+				+0.6
4,061,840	+				+0.4
4,061,841	-				+0.5
4,061,841	-				+2.2
4,061,841	-				-0.4
4,061,841	-				+0.4
4,061,939	+		Rv3622c	0.13	+0.4
4,061,940	-		Rv3622c	0.14	+0.3
4,061,940	-		Rv3622c	0.14	-0.3
4,061,940	-		Rv3622c	0.14	-0.0
4,062,004	-		Rv3622c	0.35	+0.3
4,062,014	+		Rv3622c	0.38	-0.9
4,062,014	+		Rv3622c	0.38	-0.3
4,062,201	+				+0.3
4,062,201	+				+0.3
4,062,202	-				-1.6
4,062,215	+				+0.8
4,062,233	+				+0.4
4,062,233	+				-0.4
4,062,330	-				+0.4
4,062,514	+				-0.1
4,062,839	+		Rv3623	0.43	-0.2
4,062,839	+		Rv3623	0.43	+0.0
4,062,840	-		Rv3623	0.43	-0.1