Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3566c and Rv3566A overlap by 16 nucleotides Rv3566A and Rv3567c are separated by 285 nucleotides Rv3567c and Rv3568c are separated by 14 nucleotides Rv3568c and Rv3569c overlap by 4 nucleotides
Rv3566c: Rv3566c - Arylamine N-acetyltransferase Nat (arylamine acetylase), at 4,007,331 to 4,008,182
Rv3566c
Rv3566A: Rv3566A - Hypothetical protein, at 4,008,167 to 4,008,433
Rv3566A
Rv3567c: Rv3567c - Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase., at 4,008,719 to 4,009,282
Rv3567c
Rv3568c: Rv3568c - 3,4-DHSA dioxygenase, at 4,009,297 to 4,010,199
Rv3568c
Rv3569c: Rv3569c - 4,9-DHSA hydrolase, at 4,010,196 to 4,011,071
Rv3569c
Position (kb) 4008
4009
4010 Strain fitness (log2 ratio) -1
0
1
2 at 4007.947 kb on + strand, within Rv3566c at 4007.998 kb on - strand, within Rv3566c at 4008.466 kb on - strand at 4008.971 kb on + strand, within Rv3567c at 4009.061 kb on + strand, within Rv3567c at 4009.062 kb on - strand, within Rv3567c at 4009.062 kb on - strand, within Rv3567c at 4009.118 kb on - strand, within Rv3567c at 4010.078 kb on + strand, within Rv3568c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL remove 4,007,947 + Rv3566c 0.72 -0.0 4,007,998 - Rv3566c 0.78 -0.1 4,008,466 - +0.5 4,008,971 + Rv3567c 0.45 -0.5 4,009,061 + Rv3567c 0.61 +0.1 4,009,062 - Rv3567c 0.61 +2.6 4,009,062 - Rv3567c 0.61 +0.2 4,009,118 - Rv3567c 0.71 +0.6 4,010,078 + Rv3568c 0.86 +0.7
Or see this region's nucleotide sequence