Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3557c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,996,516	+		Rv3556c	0.61	+1.1
3,996,517	-		Rv3556c	0.61	-0.0
3,996,951	+				+1.9
3,996,951	+				+0.7
3,996,952	-				-0.6
3,997,073	-				-0.7
3,997,159	+		Rv3557c	0.22	+0.9
3,997,192	+		Rv3557c	0.27	-0.4
3,997,192	+		Rv3557c	0.27	+0.3
3,997,310	-		Rv3557c	0.47	+0.5
3,997,489	+		Rv3557c	0.76	-0.1
3,997,489	+		Rv3557c	0.76	+0.6
3,997,643	-				-1.0
3,997,737	+				-1.2
3,997,737	+				-0.2
3,997,738	-				-0.8
3,997,738	-				+0.3
3,997,738	-				-0.3
3,997,738	-				-0.6
3,997,813	+				-1.0
3,997,814	-				-0.7
3,997,908	-				+0.2
3,997,908	-				-2.1
3,997,912	+				-0.2
3,998,029	-				-0.6
3,998,197	-		Rv3558	0.13	-0.4
3,998,400	+		Rv3558	0.25	-0.3
3,998,409	+		Rv3558	0.26	-0.1
3,998,410	-		Rv3558	0.26	-0.9
3,998,442	+		Rv3558	0.28	+0.4