Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3329

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,713,659	-		Rv3328c	0.28	+0.6
3,714,112	+		Rv3328c	0.76	+0.7
3,714,112	+		Rv3328c	0.76	+0.2
3,714,112	+		Rv3328c	0.76	-0.5
3,714,113	-		Rv3328c	0.77	-0.4
3,714,281	-				-0.3
3,714,352	+				-0.1
3,714,353	-				-0.1
3,714,482	+				-0.0
3,714,482	+				-0.6
3,714,482	+				+0.0
3,714,483	-				-0.3
3,714,596	+		Rv3329	0.15	-0.0
3,714,658	-		Rv3329	0.20	-0.4
3,714,658	-		Rv3329	0.20	-1.0
3,714,658	-		Rv3329	0.20	+1.4
3,714,725	+		Rv3329	0.25	-0.7
3,714,725	+		Rv3329	0.25	-0.6
3,714,726	-		Rv3329	0.25	-0.2
3,715,079	+		Rv3329	0.52	-0.3
3,715,160	+		Rv3329	0.58	-0.4
3,715,415	+		Rv3329	0.78	+1.9
3,715,539	+		Rv3329	0.87	+0.2
3,715,568	+		Rv3329	0.89	-3.0
3,715,568	+		Rv3329	0.89	+0.2
3,715,568	+		Rv3329	0.89	+1.5
3,715,569	-		Rv3329	0.89	-0.5
3,715,844	+				-1.0
3,715,892	-				-0.1
3,715,968	-		Rv3330	0.16	+0.1
3,716,263	+		Rv3330	0.40	+1.3
3,716,263	+		Rv3330	0.40	+0.3
3,716,264	-		Rv3330	0.40	-0.2
3,716,264	-		Rv3330	0.40	-0.3
3,716,264	-		Rv3330	0.40	+0.3
3,716,264	-		Rv3330	0.40	+2.5
3,716,264	-		Rv3330	0.40	-0.6
3,716,458	+		Rv3330	0.56	-0.3
3,716,458	+		Rv3330	0.56	+0.2
3,716,594	-		Rv3330	0.67	-0.7
3,716,594	-		Rv3330	0.67	-0.2
3,716,600	-		Rv3330	0.68	+0.9
3,716,630	-		Rv3330	0.70	-1.3
3,716,631	+		Rv3330	0.70	+0.4
3,716,632	-		Rv3330	0.70	-0.9
3,716,632	-		Rv3330	0.70	-0.2