Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3287c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,668,238	-				+0.1
3,668,459	+		Rv3286c	0.37	-0.3
3,668,663	+		Rv3286c	0.63	-0.6
3,668,916	-				-0.0
3,669,076	+		Rv3287c	0.29	+3.1
3,669,077	-		Rv3287c	0.29	-1.0
3,669,419	-				-0.5
3,669,473	+				+0.3
3,669,485	-				-1.9
3,669,515	+				-0.8
3,669,578	+				+0.3
3,669,578	+				-0.5
3,669,578	+				-1.0
3,669,578	+				-0.3
3,669,579	-				-0.6
3,669,579	-				+1.6
3,669,588	-				+0.6
3,669,624	-				-0.6
3,669,630	-		Rv3288c	0.11	-1.3
3,669,804	-		Rv3288c	0.53	-0.8
3,669,884	+		Rv3288c	0.72	-0.5
3,669,884	+		Rv3288c	0.72	+1.0
3,669,884	+		Rv3288c	0.72	+1.1
3,669,884	+		Rv3288c	0.72	-0.4
3,669,885	-		Rv3288c	0.72	-0.6
3,669,885	-		Rv3288c	0.72	-0.9
3,669,885	-		Rv3288c	0.72	-0.6
3,669,885	-		Rv3288c	0.72	-0.1
3,669,885	-		Rv3288c	0.72	-0.7
3,669,918	+		Rv3288c	0.80	-0.3
3,669,939	+		Rv3288c	0.85	+0.2
3,669,962	-				+0.2
3,670,001	+				-0.7
3,670,001	+				-1.5
3,670,074	-		Rv3289c	0.11	-0.7
3,670,074	-		Rv3289c	0.11	-0.3
3,670,138	+		Rv3289c	0.28	-0.2
3,670,138	+		Rv3289c	0.28	-0.2
3,670,139	-		Rv3289c	0.28	-1.3
3,670,139	-		Rv3289c	0.28	-0.6
3,670,294	+		Rv3289c	0.69	+1.4