Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3191c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,556,311	-		Rv3190c	0.70	-0.1
3,556,319	+		Rv3190c	0.71	-0.4
3,556,319	+		Rv3190c	0.71	-0.0
3,556,372	+		Rv3190c	0.75	-0.3
3,556,372	+		Rv3190c	0.75	-0.5
3,556,373	-		Rv3190c	0.75	-0.3
3,556,373	-		Rv3190c	0.75	+0.9
3,556,680	+				+0.0
3,556,690	-				-0.0
3,556,699	+				-0.5
3,556,699	+				-0.7
3,556,699	+				+0.3
3,556,699	+				-0.2
3,556,699	+				-0.7
3,556,721	+				+1.9
3,556,780	+				+0.5
3,556,860	+				-1.6
3,556,861	-				-0.3
3,556,945	+		Rv3190A	0.43	+0.3
3,556,945	+		Rv3190A	0.43	+0.0
3,556,946	-		Rv3190A	0.43	+0.6
3,556,962	+		Rv3190A	0.51	-0.5
3,556,963	-		Rv3190A	0.51	-0.2
3,556,981	+		Rv3190A	0.60	+0.3
3,556,981	+		Rv3190A	0.60	+0.1
3,556,981	+		Rv3190A	0.60	-0.4
3,556,982	-		Rv3190A	0.60	-0.5
3,556,982	-		Rv3190A	0.60	+0.4
3,557,037	+		Rv3190A	0.87	-1.3
3,557,038	-		Rv3190A	0.87	-0.5
3,557,111	-				-0.5
3,557,111	-				+0.0
3,557,143	+				-0.1
3,557,144	-				-0.2
3,557,175	+				+0.5
3,557,176	-				+0.2
3,557,251	+				-0.1
3,557,251	+				-0.3
3,557,251	+				-0.2
3,557,252	-				-0.3
3,557,252	-				-0.9
3,557,279	+				-0.5
3,557,280	-				-0.7
3,557,308	+				+0.1
3,557,308	+				-1.6
3,557,308	+				-0.6
3,557,309	-				+0.1
3,557,445	-		Rv3191c	0.13	+0.2
3,557,474	+		Rv3191c	0.16	+0.9
3,557,475	-		Rv3191c	0.16	+0.7
3,557,676	-		Rv3191c	0.35	-0.1
3,557,676	-		Rv3191c	0.35	+0.5
3,557,761	-		Rv3191c	0.43	-0.8
3,557,972	+		Rv3191c	0.64	-0.5
3,557,973	-		Rv3191c	0.64	-0.2
3,557,973	-		Rv3191c	0.64	+0.4
3,557,984	+		Rv3191c	0.65	+0.1
3,557,984	+		Rv3191c	0.65	-1.1
3,557,985	-		Rv3191c	0.65	+0.2
3,558,212	-		Rv3191c	0.87	+0.0
3,558,267	+				-0.2
3,558,268	-				+0.1
3,558,271	+				-0.0
3,558,271	+				-0.4
3,558,272	-				-0.2
3,558,272	-				-0.4
3,558,323	+				+1.2
3,558,331	-				-0.1
3,558,334	-				-0.1
3,558,334	-				+0.7
3,558,395	+				+0.1
3,558,396	-				-0.3
3,558,405	-				+1.2
3,558,693	+				+0.1
3,558,729	+				+0.9
3,558,744	-				-0.3
3,558,864	-				-0.2
3,558,864	-				-0.2
3,558,918	-				+0.1
3,558,936	-				-0.8
3,559,049	-				+0.1
3,559,162	+				+0.9
3,559,195	-				+3.4
3,559,296	-				-0.7