Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3037c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,396,459	+				-0.2
3,396,460	-				+0.3
3,396,460	-				-1.0
3,396,460	-				-0.5
3,396,460	-				-0.4
3,396,546	+		Rv3036c	0.13	-0.5
3,396,669	+		Rv3036c	0.31	+0.6
3,396,670	-		Rv3036c	0.31	+0.6
3,396,670	-		Rv3036c	0.31	+0.6
3,396,670	-		Rv3036c	0.31	-0.0
3,396,670	-		Rv3036c	0.31	-0.1
3,396,744	+		Rv3036c	0.42	+0.2
3,396,744	+		Rv3036c	0.42	-0.4
3,396,744	+		Rv3036c	0.42	-0.2
3,396,745	-		Rv3036c	0.42	-0.1
3,396,759	+		Rv3036c	0.44	-0.9
3,396,759	+		Rv3036c	0.44	+1.7
3,396,809	+		Rv3036c	0.51	-1.4
3,396,810	-		Rv3036c	0.51	-1.2
3,396,996	+		Rv3036c	0.79	-0.5
3,396,996	+		Rv3036c	0.79	-1.6
3,396,996	+		Rv3036c	0.79	+0.7
3,396,996	+		Rv3036c	0.79	+0.2
3,396,996	+		Rv3036c	0.79	+0.5
3,396,996	+		Rv3036c	0.79	-0.0
3,396,997	-		Rv3036c	0.79	+0.9
3,396,997	-		Rv3036c	0.79	-0.6
3,396,997	-		Rv3036c	0.79	-0.4
3,396,997	-		Rv3036c	0.79	-0.7
3,396,997	-		Rv3036c	0.79	-0.8
3,397,000	+		Rv3036c	0.79	-0.1
3,397,000	+		Rv3036c	0.79	+1.8
3,397,001	-		Rv3036c	0.79	-0.1
3,397,147	-				-0.4
3,397,147	-				+0.6
3,397,203	+				-0.7
3,397,236	+				+0.0
3,397,236	+				-1.6
3,397,482	+		Rv3037c	0.25	+0.1
3,397,483	-		Rv3037c	0.25	+0.9
3,397,535	+		Rv3037c	0.30	+0.3
3,397,851	+		Rv3037c	0.59	+0.0
3,398,042	+		Rv3037c	0.77	+3.4
3,398,042	+		Rv3037c	0.77	-0.0
3,398,042	+		Rv3037c	0.77	-0.1
3,398,043	-		Rv3037c	0.77	+0.1
3,398,043	-		Rv3037c	0.77	+1.4
3,398,174	+		Rv3037c	0.89	-0.4
3,398,174	+		Rv3037c	0.89	-0.3
3,398,175	-		Rv3037c	0.89	+0.2
3,398,379	+				-1.0