Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2898c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2897c and Rv2898c overlap by 1 nucleotidesRv2898c and Rv2899c are separated by 247 nucleotides Rv2897c: Rv2897c - Conserved hypothetical protein, at 3,206,431 to 3,207,942 Rv2897c Rv2898c: Rv2898c - Conserved hypothetical protein, at 3,207,942 to 3,208,328 Rv2898c Rv2899c: Rv2899c - Possible FdhD protein homolog, at 3,208,576 to 3,209,406 Rv2899c Position (kb) 3207 3208 3209Strain fitness (log2 ratio) -1 0 1at 3208.262 kb on - strand, within Rv2898cat 3208.435 kb on - strandat 3208.485 kb on + strandat 3208.485 kb on + strandat 3208.578 kb on - strandat 3209.069 kb on + strand, within Rv2899cat 3209.139 kb on - strand, within Rv2899c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL
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3,208,262 - Rv2898c 0.83 +0.4
3,208,435 - -0.5
3,208,485 + -0.1
3,208,485 + -0.3
3,208,578 - +0.5
3,209,069 + Rv2899c 0.59 -0.6
3,209,139 - Rv2899c 0.68 +0.2

Or see this region's nucleotide sequence