Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2859c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,169,774	+		Rv2858c	0.31	-0.1
3,169,775	-		Rv2858c	0.31	-0.4
3,170,440	+		Rv2858c	0.79	+0.2
3,170,718	-				+0.2
3,170,782	+				+3.4
3,170,834	+		Rv2859c	0.12	-0.0
3,170,835	-		Rv2859c	0.12	-0.1
3,170,835	-		Rv2859c	0.12	-1.2
3,170,853	-		Rv2859c	0.14	-0.1
3,171,161	+		Rv2859c	0.48	-0.0
3,171,228	+		Rv2859c	0.55	-1.1
3,171,229	-		Rv2859c	0.55	-0.5
3,171,384	+		Rv2859c	0.72	-0.8
3,171,398	-		Rv2859c	0.73	-0.9
3,171,429	+		Rv2859c	0.76	-0.2
3,171,628	+				+0.1
3,171,628	+				-0.7
3,171,648	+				-0.4
3,171,648	+				+0.8
3,171,874	+		Rv2860c	0.18	+0.6
3,171,875	-		Rv2860c	0.18	-0.2
3,172,051	+		Rv2860c	0.31	-0.5
3,172,059	-		Rv2860c	0.31	-0.4
3,172,235	-		Rv2860c	0.44	-1.2
3,172,481	-		Rv2860c	0.62	-0.6