Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2601A

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,929,256	-		Rv2601	0.55	-1.1
2,929,463	+		Rv2601	0.68	+0.4
2,929,464	-		Rv2601	0.68	+0.2
2,929,464	-		Rv2601	0.68	+0.2
2,929,464	-		Rv2601	0.68	-0.8
2,929,464	-		Rv2601	0.68	+0.2
2,929,583	-		Rv2601	0.76	+0.5
2,929,597	+		Rv2601	0.77	+0.6
2,929,597	+		Rv2601	0.77	+0.2
2,929,597	+		Rv2601	0.77	+0.3
2,929,598	-		Rv2601	0.77	-0.4
2,929,598	-		Rv2601	0.77	-1.2
2,929,598	-		Rv2601	0.77	-0.6
2,929,661	-		Rv2601	0.81	-1.0
2,929,730	-		Rv2601	0.85	-0.2
2,929,730	-		Rv2601	0.85	+0.9
2,929,782	+		Rv2601	0.89	+0.9
2,929,782	+		Rv2601	0.89	+0.4
2,929,957	+				-0.3
2,929,970	+				-0.3
2,929,970	+				-0.0
2,930,049	+				+0.2
2,930,423	+		Rv2602	0.18	-0.2
2,930,519	-		Rv2602	0.40	-0.2
2,930,683	+		Rv2602	0.77	+0.3
2,930,684	-		Rv2602	0.77	-1.1
2,930,684	-		Rv2602	0.77	-1.3
2,930,684	-		Rv2602	0.77	+0.1
2,930,684	-		Rv2602	0.77	-0.5
2,930,687	+		Rv2602	0.78	+0.1
2,930,687	+		Rv2602	0.78	+0.5
2,930,703	+		Rv2602	0.81	-0.3
2,930,704	-		Rv2602	0.82	+2.9
2,930,749	+				-0.2
2,930,750	-				+0.2