Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2463

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,764,853	+		Rv2462c	0.69	-0.2
2,764,854	-		Rv2462c	0.69	-0.5
2,764,857	+		Rv2462c	0.69	+0.1
2,764,857	+		Rv2462c	0.69	+0.3
2,764,857	+		Rv2462c	0.69	+0.3
2,764,994	-		Rv2462c	0.79	-0.5
2,765,198	-				+0.8
2,765,516	+				+0.0
2,765,516	+				-0.4
2,765,536	+				+0.0
2,765,536	+				-0.4
2,765,536	+				-0.3
2,765,536	+				-0.1
2,765,704	+				+0.3
2,766,129	+		Rv2463	0.40	-0.7
2,766,189	-		Rv2463	0.45	-0.4
2,766,201	+		Rv2463	0.46	+0.7
2,766,202	-		Rv2463	0.46	-0.7
2,766,287	-		Rv2463	0.53	-0.2
2,766,352	+		Rv2463	0.59	-2.4
2,766,498	+		Rv2463	0.71	-0.3
2,766,499	-		Rv2463	0.71	-0.8
2,766,499	-		Rv2463	0.71	-1.6
2,766,499	-		Rv2463	0.71	+0.5
2,766,499	-		Rv2463	0.71	+0.6
2,766,627	+		Rv2463	0.82	+1.1
2,766,627	+		Rv2463	0.82	-0.1
2,766,627	+		Rv2463	0.82	-0.8
2,766,627	+		Rv2463	0.82	-0.8
2,766,627	+		Rv2463	0.82	-1.1
2,766,627	+		Rv2463	0.82	+1.1
2,766,628	-		Rv2463	0.82	-1.1
2,766,739	-				-2.1
2,766,826	+				+0.3
2,766,827	-				-0.6
2,766,837	+				-0.5
2,766,965	+		Rv2464c	0.13	+0.2
2,766,965	+		Rv2464c	0.13	-0.2
2,766,965	+		Rv2464c	0.13	-1.9
2,766,965	+		Rv2464c	0.13	-0.7
2,766,965	+		Rv2464c	0.13	+0.3
2,766,965	+		Rv2464c	0.13	+1.1
2,766,965	+		Rv2464c	0.13	-0.4
2,766,966	-		Rv2464c	0.13	-0.2
2,766,966	-		Rv2464c	0.13	+0.7
2,766,966	-		Rv2464c	0.13	-0.4
2,766,966	-		Rv2464c	0.13	+1.2
2,766,966	-		Rv2464c	0.13	-0.3
2,766,966	-		Rv2464c	0.13	-0.1
2,766,966	-		Rv2464c	0.13	-0.1
2,766,966	-		Rv2464c	0.13	+0.5
2,766,989	+		Rv2464c	0.16	+0.3
2,766,989	+		Rv2464c	0.16	+1.9
2,766,990	-		Rv2464c	0.16	-0.6
2,767,013	+		Rv2464c	0.19	+0.5
2,767,164	-		Rv2464c	0.38	-0.0
2,767,213	+		Rv2464c	0.44	-0.3
2,767,454	+		Rv2464c	0.74	-1.6
2,767,455	-		Rv2464c	0.74	+0.3
2,767,455	-		Rv2464c	0.74	+0.2
2,767,493	+		Rv2464c	0.79	+0.4
2,767,493	+		Rv2464c	0.79	+0.1
2,767,494	-		Rv2464c	0.79	-0.3
2,767,650	+				-2.3
2,767,650	+				-0.3
2,767,651	-				-0.0