Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2236c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,507,528	-		Rv2234	0.78	-0.7
2,507,528	-		Rv2234	0.78	+1.3
2,507,530	+		Rv2234	0.78	+0.0
2,508,451	-				-0.7
2,509,208	+		Rv2236c	0.82	-1.3
2,509,208	+		Rv2236c	0.82	-0.4
2,509,236	+		Rv2236c	0.85	-1.2
2,509,236	+		Rv2236c	0.85	-0.6
2,509,236	+		Rv2236c	0.85	-0.4
2,509,400	+				-0.3
2,509,401	-				-0.3
2,509,410	+				-1.4
2,509,414	+				-0.6
2,509,424	+				-1.4
2,509,433	+				+0.0
2,509,582	+		Rv2237	0.12	-0.4
2,509,582	+		Rv2237	0.12	-0.2
2,509,583	-		Rv2237	0.12	-0.2
2,509,621	+		Rv2237	0.17	-0.2
2,509,622	-		Rv2237	0.17	-0.3
2,509,622	-		Rv2237	0.17	-0.4
2,509,729	+		Rv2237	0.31	+0.5
2,509,730	-		Rv2237	0.31	+0.2
2,509,732	-		Rv2237	0.32	-1.2
2,509,777	+		Rv2237	0.38	-0.3
2,509,783	+		Rv2237	0.38	-1.2
2,510,151	-		Rv2237	0.86	+0.9
2,510,207	-				+0.4