Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2213

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,477,356	+		Rv2212	0.15	+0.2
2,477,356	+		Rv2212	0.15	+1.3
2,477,376	+		Rv2212	0.16	+0.1
2,477,377	-		Rv2212	0.16	-0.2
2,477,377	-		Rv2212	0.16	-0.2
2,477,377	-		Rv2212	0.16	-0.1
2,477,682	+		Rv2212	0.43	-1.0
2,477,766	+		Rv2212	0.51	-0.1
2,478,072	+		Rv2212	0.78	-0.7
2,478,102	+		Rv2212	0.80	-0.7
2,478,102	+		Rv2212	0.80	-0.3
2,478,325	-				+0.0
2,478,360	+				-1.9
2,478,360	+				-0.4
2,478,361	-				-1.5
2,478,361	-				-1.9
2,478,361	-				-0.2
2,478,727	-		Rv2213	0.25	-0.8
2,478,727	-		Rv2213	0.25	-2.1
2,478,780	-		Rv2213	0.29	-0.4
2,479,481	+		Rv2213	0.74	-1.1
2,479,482	-		Rv2213	0.74	-1.2
2,479,784	+				-0.6
2,479,784	+				-0.7
2,479,784	+				-0.2
2,479,785	-				-0.8
2,479,925	-				-0.1
2,479,947	-				-1.2
2,479,984	+				-0.5
2,479,985	-				+0.0
2,479,986	+				-0.4
2,479,993	+				-0.3
2,479,993	+				-0.2
2,480,074	+				-0.9
2,480,074	+				+0.3
2,480,257	+		Rv2214c	0.19	-0.0
2,480,257	+		Rv2214c	0.19	+0.3
2,480,258	-		Rv2214c	0.19	-0.2
2,480,258	-		Rv2214c	0.19	+0.2
2,480,258	-		Rv2214c	0.19	-0.7
2,480,258	-		Rv2214c	0.19	-0.2
2,480,308	+		Rv2214c	0.22	+0.5
2,480,569	+		Rv2214c	0.36	+1.2
2,480,569	+		Rv2214c	0.36	-0.2
2,480,569	+		Rv2214c	0.36	-0.4
2,480,569	+		Rv2214c	0.36	-0.2
2,480,770	-		Rv2214c	0.48	-0.1