Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1773c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,006,197	-		Rv1771	0.80	+0.2
2,006,215	-		Rv1771	0.82	+0.5
2,006,233	-		Rv1771	0.83	+0.9
2,006,256	+		Rv1771	0.85	-0.3
2,006,257	-		Rv1771	0.85	-0.1
2,006,313	-		Rv1771	0.90	-0.1
2,006,523	+				-0.6
2,006,531	-				-0.4
2,006,946	-				-0.9
2,007,425	+		Rv1773c	0.54	+0.3
2,007,498	-		Rv1773c	0.64	+1.6
2,007,653	+		Rv1773c	0.85	-0.1
2,007,653	+		Rv1773c	0.85	+0.7
2,007,680	+		Rv1773c	0.88	+1.2
2,007,757	+				-0.4
2,007,758	-				+0.1
2,007,778	-				+1.3
2,007,831	+				-0.4
2,007,831	+				-1.3
2,007,831	+				-0.1
2,007,831	+				+1.9
2,007,831	+				+0.8
2,008,009	-		Rv1774	0.13	+0.2
2,008,417	+		Rv1774	0.44	+0.3
2,008,417	+		Rv1774	0.44	+0.6
2,008,462	+		Rv1774	0.47	+0.2
2,008,462	+		Rv1774	0.47	-0.2
2,008,706	-		Rv1774	0.65	+0.7
2,008,706	-		Rv1774	0.65	-0.4
2,008,708	-		Rv1774	0.65	-0.1
2,008,754	-		Rv1774	0.69	+0.4