Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1635c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
1,839,821	-		Rv1634	0.46	+2.7
1,839,976	+		Rv1634	0.57	+0.6
1,839,976	+		Rv1634	0.57	+2.3
1,839,976	+		Rv1634	0.57	+1.5
1,839,977	-		Rv1634	0.57	+2.4
1,840,006	-		Rv1634	0.59	+2.2
1,840,046	+		Rv1634	0.62	+2.2
1,840,050	+		Rv1634	0.62	+2.9
1,840,050	+		Rv1634	0.62	+3.0
1,840,050	+		Rv1634	0.62	+2.5
1,840,050	+		Rv1634	0.62	+2.8
1,840,050	+		Rv1634	0.62	+2.6
1,840,050	+		Rv1634	0.62	+2.4
1,840,050	+		Rv1634	0.62	+2.6
1,840,050	+		Rv1634	0.62	+2.8
1,840,050	+		Rv1634	0.62	+2.9
1,840,051	-		Rv1634	0.62	+2.9
1,840,178	+		Rv1634	0.71	+2.7
1,840,349	+		Rv1634	0.83	+2.5
1,840,408	+		Rv1634	0.88	+2.6
1,840,409	-		Rv1634	0.88	+4.9
1,840,409	-		Rv1634	0.88	+2.9
1,840,498	+				+3.2
1,840,500	+				+2.5
1,840,500	+				+4.6
1,840,500	+				+3.1
1,840,500	+				+2.0
1,840,500	+				+1.4
1,840,501	-				+3.2
1,840,501	-				+1.1
1,840,501	-				+2.7
1,840,501	-				+2.6
1,840,501	-				+2.5
1,840,501	-				+0.1
1,840,501	-				+1.2
1,840,501	-				+2.8
1,840,501	-				+2.8
1,840,501	-				+2.6
1,840,546	-				+1.9
1,840,600	+				-0.6
1,840,600	+				-0.4
1,840,601	-				-0.3
1,840,640	-				-0.0
1,840,640	-				-0.2
1,840,655	-				-0.2
1,840,655	-				-0.5
1,840,656	+				-0.2
1,840,656	+				-0.4
1,840,779	-		Rv1635c	0.12	-1.5
1,840,828	+		Rv1635c	0.15	-0.5
1,840,828	+		Rv1635c	0.15	-1.1
1,840,829	-		Rv1635c	0.15	-0.7
1,840,829	-		Rv1635c	0.15	-0.5
1,840,984	+		Rv1635c	0.25	-1.8
1,840,985	-		Rv1635c	0.25	-2.1
1,841,006	-		Rv1635c	0.26	-0.6
1,841,029	+		Rv1635c	0.27	-0.7
1,841,161	+		Rv1635c	0.35	-0.9
1,841,162	-		Rv1635c	0.35	-0.2
1,841,164	+		Rv1635c	0.35	-1.3
1,841,188	+		Rv1635c	0.37	-0.8
1,841,252	+		Rv1635c	0.41	-1.1
1,841,351	-		Rv1635c	0.47	-0.7
1,841,351	-		Rv1635c	0.47	-0.2
1,841,361	+		Rv1635c	0.47	-0.1
1,841,362	-		Rv1635c	0.47	-0.6
1,841,362	-		Rv1635c	0.47	-0.5
1,841,362	-		Rv1635c	0.47	-0.4
1,841,362	-		Rv1635c	0.47	-0.1
1,841,436	+		Rv1635c	0.52	-1.6
1,841,436	+		Rv1635c	0.52	-0.3
1,841,437	-		Rv1635c	0.52	-0.7
1,841,437	-		Rv1635c	0.52	-1.1
1,841,437	-		Rv1635c	0.52	-0.3
1,841,543	-		Rv1635c	0.58	-1.4
1,841,543	-		Rv1635c	0.58	+0.0
1,841,543	-		Rv1635c	0.58	-0.7
1,841,570	+		Rv1635c	0.60	-0.7
1,841,605	+		Rv1635c	0.62	+1.9
1,841,652	+		Rv1635c	0.65	-1.5
1,841,655	+		Rv1635c	0.65	-0.9
1,841,656	-		Rv1635c	0.65	-1.0
1,841,679	+		Rv1635c	0.66	-0.2
1,841,851	-		Rv1635c	0.77	-0.7
1,841,868	+		Rv1635c	0.78	-0.2
1,841,868	+		Rv1635c	0.78	-2.1
1,841,896	+		Rv1635c	0.79	-1.4
1,841,896	+		Rv1635c	0.79	-0.6
1,841,896	+		Rv1635c	0.79	-0.9
1,841,897	-		Rv1635c	0.79	-0.5
1,841,897	-		Rv1635c	0.79	-0.6
1,841,899	+		Rv1635c	0.79	+0.1
1,841,922	-		Rv1635c	0.81	-0.4
1,841,940	+		Rv1635c	0.82	-0.7
1,841,940	+		Rv1635c	0.82	-0.7
1,841,940	+		Rv1635c	0.82	+0.7
1,841,941	-		Rv1635c	0.82	+0.5
1,841,941	-		Rv1635c	0.82	-1.0
1,842,155	+				+1.5
1,842,387	+				-1.7
1,842,391	+				-0.3
1,842,391	+				+0.1
1,842,391	+				-0.2
1,842,391	+				-0.1
1,842,426	+				+0.9
1,842,426	+				+0.5
1,842,890	-				-0.0
1,842,899	+				+0.1
1,842,974	+				-0.4
1,842,975	-				-0.1
1,842,975	-				-0.6
1,842,995	+		Rv1637c	0.12	-0.4
1,842,996	-		Rv1637c	0.12	+1.9