Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0721 and Rv0722 are separated by 2 nucleotides Rv0722 and Rv0723 overlap by 1 nucleotides Rv0723 and Rv0724 are separated by 32 nucleotides Rv0724 and Rv0724A overlap by 4 nucleotides Rv0724A and Rv0725c overlap by 328 nucleotides
Rv0721: Rv0721 - 30S ribosomal protein S5 RpsE, at 814,328 to 814,990
Rv0721
Rv0722: Rv0722 - 50S ribosomal protein L30 RpmD, at 814,993 to 815,190
Rv0722
Rv0723: Rv0723 - 50S ribosomal protein L15 RplO, at 815,190 to 815,630
Rv0723
Rv0724: Rv0724 - Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase), at 815,663 to 817,534
Rv0724
Rv0724A: Rv0724A - Conserved hypothetical protein, at 817,531 to 817,866
Rv0724A
Rv0725c: Rv0725c - Conserved hypothetical protein, at 817,539 to 818,444
Rv0725c
Position (kb) 815
816
817
818 Strain fitness (log2 ratio) -1
0
1 at 814.988 kb on + strand at 814.988 kb on + strand at 815.628 kb on + strand at 815.629 kb on - strand at 815.718 kb on + strand at 815.719 kb on - strand at 815.731 kb on + strand at 815.731 kb on + strand at 815.732 kb on - strand at 815.772 kb on + strand at 815.772 kb on + strand at 815.817 kb on + strand at 815.887 kb on + strand, within Rv0724 at 816.107 kb on + strand, within Rv0724 at 816.108 kb on - strand, within Rv0724 at 816.417 kb on + strand, within Rv0724 at 816.798 kb on + strand, within Rv0724 at 817.151 kb on + strand, within Rv0724 at 817.151 kb on + strand, within Rv0724 at 817.151 kb on + strand, within Rv0724 at 817.323 kb on + strand, within Rv0724 at 817.352 kb on - strand at 817.622 kb on - strand at 817.700 kb on + strand at 817.701 kb on - strand at 817.880 kb on - strand, within Rv0725c at 817.975 kb on + strand, within Rv0725c at 818.171 kb on - strand, within Rv0725c at 818.256 kb on - strand, within Rv0725c at 818.453 kb on + strand at 818.453 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Pretomanid 0.213 ug/mL remove 814,988 + -0.0 814,988 + +0.1 815,628 + -0.7 815,629 - +0.1 815,718 + -0.1 815,719 - +0.0 815,731 + -0.0 815,731 + +0.2 815,732 - -1.1 815,772 + +0.1 815,772 + +0.8 815,817 + -0.4 815,887 + Rv0724 0.12 -0.4 816,107 + Rv0724 0.24 +0.3 816,108 - Rv0724 0.24 +1.1 816,417 + Rv0724 0.40 -1.5 816,798 + Rv0724 0.61 -0.3 817,151 + Rv0724 0.79 -0.5 817,151 + Rv0724 0.79 -0.4 817,151 + Rv0724 0.79 -0.6 817,323 + Rv0724 0.89 -1.2 817,352 - +0.7 817,622 - +0.6 817,700 + -0.1 817,701 - +0.2 817,880 - Rv0725c 0.38 -0.7 817,975 + Rv0725c 0.48 -0.7 818,171 - Rv0725c 0.70 -0.3 818,256 - Rv0725c 0.79 +0.7 818,453 + -0.1 818,453 + +0.3
Or see this region's nucleotide sequence