Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3697c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
4,139,762	+				+1.6
4,139,831	+				+1.7
4,139,831	+				+1.6
4,139,831	+				+0.1
4,140,097	-		Rv3697c	0.67	-1.8
4,140,100	+		Rv3697c	0.67	-0.6
4,140,127	+		Rv3697c	0.74	-0.2
4,140,127	+		Rv3697c	0.74	-1.9
4,140,127	+		Rv3697c	0.74	+1.3
4,140,128	-		Rv3697c	0.74	-0.7
4,140,129	+		Rv3697c	0.74	-1.0
4,140,129	+		Rv3697c	0.74	-0.2
4,140,130	-		Rv3697c	0.74	-0.4
4,140,463	+				+0.3
4,140,464	-				+0.4
4,140,484	-				-0.8
4,140,577	+				-0.1
4,140,578	-				-0.5
4,140,746	-		Rv3698	0.17	-1.1
4,140,746	-		Rv3698	0.17	+0.8
4,140,746	-		Rv3698	0.17	-2.0
4,140,788	+		Rv3698	0.19	-1.4
4,140,796	+		Rv3698	0.20	-1.6
4,140,796	+		Rv3698	0.20	-0.0
4,140,797	-		Rv3698	0.20	-2.5
4,141,203	-		Rv3698	0.46	-0.4