Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3403c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,821,276	-		Rv3402c	0.50	+0.2
3,821,276	-		Rv3402c	0.50	-0.1
3,821,316	+		Rv3402c	0.54	-1.3
3,821,552	-		Rv3402c	0.73	+0.1
3,821,650	+		Rv3402c	0.80	-0.8
3,821,701	+		Rv3402c	0.85	-0.3
3,821,701	+		Rv3402c	0.85	-0.9
3,821,724	+		Rv3402c	0.86	-0.0
3,821,724	+		Rv3402c	0.86	-0.3
3,821,725	-		Rv3402c	0.87	-0.1
3,821,814	+				+0.0
3,821,841	+				-0.1
3,821,891	+				-0.2
3,821,892	-				-0.1
3,821,892	-				+0.3
3,821,892	-				-1.0
3,821,893	+				+0.4
3,821,893	+				-0.7
3,821,893	+				+0.3
3,821,893	+				+0.6
3,821,894	-				+1.9
3,821,985	+				-0.1
3,822,033	-				-0.3
3,822,185	-				-0.3
3,822,579	+		Rv3403c	0.20	+0.1
3,822,580	-		Rv3403c	0.20	+0.1
3,822,580	-		Rv3403c	0.20	-0.4
3,822,580	-		Rv3403c	0.20	+0.4
3,822,580	-		Rv3403c	0.20	-0.1
3,822,603	-		Rv3403c	0.21	+0.0
3,822,652	+		Rv3403c	0.24	+0.2
3,822,652	+		Rv3403c	0.24	-0.1
3,822,653	-		Rv3403c	0.24	-0.0
3,822,837	-		Rv3403c	0.36	-0.6
3,822,927	+		Rv3403c	0.42	+0.3
3,822,987	-		Rv3403c	0.45	+0.6
3,822,987	-		Rv3403c	0.45	+0.6
3,822,987	-		Rv3403c	0.45	-0.1
3,823,060	+		Rv3403c	0.50	-0.1
3,823,061	-		Rv3403c	0.50	-0.3
3,823,061	-		Rv3403c	0.50	+1.9
3,823,064	+		Rv3403c	0.50	-0.0
3,823,065	-		Rv3403c	0.50	-1.6
3,823,106	-		Rv3403c	0.53	+0.7
3,823,106	-		Rv3403c	0.53	-0.3
3,823,185	-		Rv3403c	0.58	+0.0
3,823,197	+		Rv3403c	0.58	-0.4
3,823,198	-		Rv3403c	0.58	+0.3
3,823,199	+		Rv3403c	0.58	+1.5
3,823,199	+		Rv3403c	0.58	-1.0
3,823,199	+		Rv3403c	0.58	-0.2
3,823,199	+		Rv3403c	0.58	+0.1
3,823,199	+		Rv3403c	0.58	-0.7
3,823,199	+		Rv3403c	0.58	+0.1
3,823,200	-		Rv3403c	0.59	-0.2
3,823,200	-		Rv3403c	0.59	-1.2
3,823,200	-		Rv3403c	0.59	-0.1
3,823,326	-		Rv3403c	0.66	+0.0
3,823,439	-		Rv3403c	0.73	+0.3
3,823,439	-		Rv3403c	0.73	+0.1
3,823,463	+		Rv3403c	0.75	-0.8
3,823,464	-		Rv3403c	0.75	+0.6
3,823,779	+				+0.3
3,823,779	+				-0.5
3,823,779	+				-0.7
3,823,779	+				+0.8
3,823,780	-				+0.4
3,823,821	+				-0.3
3,823,821	+				+1.3
3,823,821	+				+0.4
3,823,821	+				-0.1
3,823,821	+				-0.7
3,823,822	-				+0.4
3,823,822	-				-0.3
3,823,822	-				+0.1
3,823,836	+				-0.0
3,823,836	+				-0.5
3,823,837	-				-0.2
3,823,837	-				-0.9
3,823,837	-				-0.2
3,823,859	-				+0.2
3,824,095	+		Rv3404c	0.30	-0.6
3,824,103	+		Rv3404c	0.32	+0.3
3,824,103	+		Rv3404c	0.32	+0.2
3,824,103	+		Rv3404c	0.32	-0.0
3,824,103	+		Rv3404c	0.32	-0.0
3,824,103	+		Rv3404c	0.32	-0.1
3,824,104	-		Rv3404c	0.32	+0.3
3,824,104	-		Rv3404c	0.32	+0.1
3,824,104	-		Rv3404c	0.32	-0.2
3,824,104	-		Rv3404c	0.32	+1.0
3,824,104	-		Rv3404c	0.32	-0.7
3,824,172	+		Rv3404c	0.41	+0.1
3,824,326	-		Rv3404c	0.63	+0.3
3,824,326	-		Rv3404c	0.63	+0.3
3,824,395	+		Rv3404c	0.73	+0.1
3,824,396	-		Rv3404c	0.73	+0.1
3,824,396	-		Rv3404c	0.73	-0.1
3,824,421	+		Rv3404c	0.77	-0.4
3,824,499	+		Rv3404c	0.88	+1.1
3,824,499	+		Rv3404c	0.88	-0.2
3,824,499	+		Rv3404c	0.88	+0.1
3,824,510	-		Rv3404c	0.89	+0.4
3,824,576	+				-1.1
3,824,577	-				+0.0
3,824,645	+				-0.4
3,824,664	-				-0.6
3,824,750	+				+1.5
3,824,750	+				-0.7
3,824,750	+				+0.9
3,824,750	+				-0.2
3,824,751	-				+0.0
3,824,751	-				+1.2
3,824,751	-				-1.1