Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3262
Experiment: 7H9 with Pretomanid 0.213 ug/mL
Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.
Per-strain Table
Position | Strand | Gene | LocusTag | Fraction | 7H9 with Pretomanid 0.213 ug/mL |
---|---|---|---|---|---|
remove | |||||
3,640,741 | + | Rv3261 | 0.20 | +3.9 | |
3,640,742 | - | Rv3261 | 0.20 | +4.7 | |
3,640,742 | - | Rv3261 | 0.20 | +2.1 | |
3,640,742 | - | Rv3261 | 0.20 | +4.5 | |
3,641,003 | + | Rv3261 | 0.46 | +5.4 | |
3,641,887 | + | Rv3262 | 0.26 | +4.5 | |
3,642,060 | + | Rv3262 | 0.39 | +3.0 | |
3,642,061 | - | Rv3262 | 0.39 | +2.6 | |
3,642,526 | + | Rv3262 | 0.74 | +3.2 | |
3,643,037 | + | +0.5 | |||
3,643,114 | + | +0.2 | |||
3,643,114 | + | -1.7 | |||
3,643,115 | - | -0.3 | |||
3,643,219 | + | +0.5 | |||
3,643,220 | - | +0.9 | |||
3,643,240 | - | -0.4 | |||
3,643,240 | - | +1.1 | |||
3,643,240 | - | +0.2 | |||
3,643,304 | - | -0.4 | |||
3,643,306 | + | +0.4 | |||
3,643,306 | + | -0.1 | |||
3,643,306 | + | -0.8 | |||
3,643,307 | - | +0.6 | |||
3,643,507 | - | Rv3263 | 0.20 | +0.1 | |
3,643,634 | + | Rv3263 | 0.27 | +0.1 | |
3,643,764 | - | Rv3263 | 0.35 | +0.4 | |
3,643,764 | - | Rv3263 | 0.35 | +1.2 | |
3,643,807 | - | Rv3263 | 0.38 | -0.2 |
Or see this region's nucleotide sequence