Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2959c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,311,192	+		Rv2958c	0.37	+0.4
3,311,193	-		Rv2958c	0.37	+0.1
3,311,193	-		Rv2958c	0.37	-0.3
3,311,193	-		Rv2958c	0.37	+0.1
3,311,196	+		Rv2958c	0.37	-0.5
3,311,197	-		Rv2958c	0.38	-1.0
3,311,242	+		Rv2958c	0.41	-0.1
3,311,273	+		Rv2958c	0.43	-0.4
3,311,275	+		Rv2958c	0.44	+0.6
3,311,297	+		Rv2958c	0.45	+0.3
3,311,297	+		Rv2958c	0.45	-0.6
3,311,297	+		Rv2958c	0.45	-0.2
3,311,297	+		Rv2958c	0.45	+0.2
3,311,297	+		Rv2958c	0.45	+0.1
3,311,297	+		Rv2958c	0.45	-0.3
3,311,297	+		Rv2958c	0.45	-0.2
3,311,298	-		Rv2958c	0.45	+0.4
3,311,298	-		Rv2958c	0.45	-0.3
3,311,318	-		Rv2958c	0.47	+0.0
3,311,327	+		Rv2958c	0.48	-0.3
3,311,327	+		Rv2958c	0.48	-0.3
3,311,327	+		Rv2958c	0.48	+0.0
3,311,328	-		Rv2958c	0.48	+1.6
3,311,336	+		Rv2958c	0.48	+0.3
3,311,337	-		Rv2958c	0.48	+0.3
3,311,423	+		Rv2958c	0.55	-0.2
3,311,456	+		Rv2958c	0.58	-0.6
3,311,543	+		Rv2958c	0.64	+2.1
3,311,564	+		Rv2958c	0.66	-0.4
3,311,564	+		Rv2958c	0.66	-0.3
3,311,564	+		Rv2958c	0.66	+0.4
3,311,564	+		Rv2958c	0.66	+0.4
3,311,565	-		Rv2958c	0.66	-0.1
3,311,623	+		Rv2958c	0.71	+0.7
3,311,623	+		Rv2958c	0.71	-0.1
3,311,624	-		Rv2958c	0.71	-0.1
3,311,624	-		Rv2958c	0.71	-0.6
3,311,669	+		Rv2958c	0.74	-0.6
3,311,670	-		Rv2958c	0.74	-0.6
3,311,670	-		Rv2958c	0.74	-0.2
3,311,670	-		Rv2958c	0.74	-0.3
3,311,693	+		Rv2958c	0.76	-0.4
3,311,694	-		Rv2958c	0.76	-0.5
3,311,694	-		Rv2958c	0.76	-0.0
3,311,694	-		Rv2958c	0.76	+0.3
3,311,694	-		Rv2958c	0.76	-0.2
3,311,787	+		Rv2958c	0.83	-1.5
3,311,822	+		Rv2958c	0.86	-0.0
3,311,823	-		Rv2958c	0.86	+0.0
3,312,184	+		Rv2959c	0.11	+0.7
3,312,279	-		Rv2959c	0.24	-0.6
3,312,282	+		Rv2959c	0.25	+1.4
3,312,505	+		Rv2959c	0.55	-1.9
3,312,505	+		Rv2959c	0.55	+1.4
3,312,506	-		Rv2959c	0.55	+0.4
3,312,506	-		Rv2959c	0.55	+0.4
3,312,506	-		Rv2959c	0.55	-0.1
3,312,506	-		Rv2959c	0.55	-0.1
3,312,509	+		Rv2959c	0.55	-0.3
3,312,509	+		Rv2959c	0.55	+0.0
3,312,552	+		Rv2959c	0.61	-0.3
3,312,553	-		Rv2959c	0.61	+0.4
3,312,553	-		Rv2959c	0.61	+0.6
3,312,571	-		Rv2959c	0.64	-0.3
3,312,627	+		Rv2959c	0.71	+0.7
3,312,901	+				+0.2
3,312,933	+				+0.3
3,312,933	+				+1.8
3,312,933	+				-0.4
3,312,934	-				-0.4
3,313,020	-		Rv2960c	0.27	-2.2
3,313,077	+		Rv2960c	0.50	+0.8
3,313,077	+		Rv2960c	0.50	+0.1
3,313,077	+		Rv2960c	0.50	-0.1
3,313,077	+		Rv2960c	0.50	-2.3
3,313,094	+		Rv2960c	0.57	-0.3
3,313,170	-		Rv2960c	0.87	-0.3
3,313,178	+				-1.0
3,313,179	-				-0.0
3,313,318	-				+0.3
3,313,431	+		Rv2961	0.38	-0.0
3,313,432	-		Rv2961	0.38	+0.1
3,313,436	-		Rv2961	0.39	-0.1
3,313,770	+				-1.1