Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2901c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
3,211,225	+		Rv2900c	0.78	-0.3
3,211,225	+		Rv2900c	0.78	-0.8
3,211,226	-		Rv2900c	0.78	-0.5
3,211,226	-		Rv2900c	0.78	+0.5
3,211,226	-		Rv2900c	0.78	-1.2
3,211,283	-		Rv2900c	0.80	+0.3
3,211,434	-		Rv2900c	0.87	+0.2
3,211,544	+				-0.4
3,211,617	+				+0.2
3,211,618	-				-0.9
3,211,741	+				-0.4
3,211,741	+				+0.3
3,211,741	+				-2.2
3,211,741	+				-0.8
3,211,742	-				-0.4
3,211,742	-				-0.4
3,211,742	-				-0.6
3,211,804	+				-0.3
3,211,804	+				+0.1
3,211,805	-				-0.0
3,211,805	-				-0.3
3,211,900	+		Rv2901c	0.32	+0.3
3,211,943	-		Rv2901c	0.46	-0.3
3,211,993	+		Rv2901c	0.62	+0.0
3,212,013	+		Rv2901c	0.69	+1.2
3,212,014	-		Rv2901c	0.69	+0.9
3,212,084	-				+0.5
3,212,163	+				+2.2
3,212,164	-				-1.1
3,212,164	-				-0.0
3,212,328	+		Rv2902c	0.21	+0.3
3,212,329	-		Rv2902c	0.21	-0.9
3,212,389	-		Rv2902c	0.29	+0.2
3,212,611	+		Rv2902c	0.56	+0.4
3,212,611	+		Rv2902c	0.56	+0.5
3,212,612	-		Rv2902c	0.57	-1.1
3,212,612	-		Rv2902c	0.57	-0.6
3,212,612	-		Rv2902c	0.57	+2.6
3,212,679	+		Rv2902c	0.65	-0.4
3,212,680	-		Rv2902c	0.65	+0.1
3,212,771	+		Rv2902c	0.77	+1.6
3,212,921	-				+0.1
3,212,957	-				-0.7