Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2659c

Experiment: 7H9 with Pretomanid 0.213 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Pretomanid 0.213 ug/mL
2,978,741	+		Rv2656c	0.21	-0.1
2,978,916	+		Rv2656c	0.65	-0.4
2,978,916	+		Rv2656c	0.65	+0.0
2,978,916	+		Rv2656c	0.65	-1.5
2,979,188	+		Rv2657c	0.53	-1.7
2,979,188	+		Rv2657c	0.53	-0.4
2,979,335	+				+0.1
2,979,356	+				-1.1
2,979,356	+				+0.3
2,979,356	+				+0.0
2,979,356	+				+0.0
2,979,356	+				+0.0
2,979,374	+		Rv2658c	0.13	-0.7
2,979,392	+		Rv2658c	0.18	-0.5
2,979,393	-		Rv2658c	0.18	+0.2
2,979,393	-		Rv2658c	0.18	-0.6
2,979,498	+		Rv2658c	0.47	-1.2
2,979,584	+		Rv2658c	0.71	-0.4
2,979,584	+		Rv2658c	0.71	-0.5
2,979,584	+		Rv2658c	0.71	-0.0
2,979,585	-		Rv2658c	0.71	-0.5
2,979,585	-		Rv2658c	0.71	-0.6
2,979,585	-		Rv2658c	0.71	-0.3
2,979,662	-				-1.5
2,979,662	-				+0.4
2,979,662	-				-0.3
2,979,665	+				+0.4
2,979,665	+				+0.0
2,979,665	+				+1.4
2,979,674	-				-0.6
2,979,799	+				+1.9
2,979,914	+		Rv2659c	0.20	+0.5
2,979,914	+		Rv2659c	0.20	-0.2
2,979,926	+		Rv2659c	0.21	-0.1
2,979,943	+		Rv2659c	0.22	+0.4
2,979,943	+		Rv2659c	0.22	+1.6
2,979,943	+		Rv2659c	0.22	+0.1
2,979,944	-		Rv2659c	0.22	-0.9
2,979,944	-		Rv2659c	0.22	+0.8
2,979,944	-		Rv2659c	0.22	+1.2
2,979,944	-		Rv2659c	0.22	+0.9
2,980,051	-		Rv2659c	0.32	-1.1
2,980,055	-		Rv2659c	0.32	+1.9
2,980,171	+		Rv2659c	0.43	+0.4
2,980,394	+		Rv2659c	0.62	+0.3
2,980,395	-		Rv2659c	0.62	-0.3
2,980,440	-		Rv2659c	0.66	-0.2
2,980,527	-		Rv2659c	0.74	-0.2
2,980,580	+		Rv2659c	0.79	-0.2
2,980,633	+		Rv2659c	0.84	-1.2
2,980,633	+		Rv2659c	0.84	-0.1
2,980,633	+		Rv2659c	0.84	+2.4
2,980,633	+		Rv2659c	0.84	+0.3
2,980,633	+		Rv2659c	0.84	-0.0
2,980,633	+		Rv2659c	0.84	+1.4
2,980,634	-		Rv2659c	0.84	-0.2
2,980,634	-		Rv2659c	0.84	-0.4
2,980,634	-		Rv2659c	0.84	-0.5
2,980,634	-		Rv2659c	0.84	-1.1
2,980,634	-		Rv2659c	0.84	-0.7
2,980,634	-		Rv2659c	0.84	-1.5
2,980,715	+				-0.2
2,980,715	+				+0.5
2,980,715	+				-0.1
2,980,715	+				-0.7
2,980,716	-				+0.3
2,980,740	-				+0.0
2,980,852	+				+0.2
2,981,043	+		Rv2660c	0.35	+0.2
2,981,044	-		Rv2660c	0.36	-0.6
2,981,044	-		Rv2660c	0.36	+2.6
2,981,044	-		Rv2660c	0.36	-0.3
2,981,416	-		Rv2661c	0.59	-0.0
2,981,466	-		Rv2661c	0.72	+0.9
2,981,584	+		Rv2662	0.37	+0.1
2,981,585	-		Rv2662	0.38	+0.2
2,981,627	+		Rv2662	0.53	-0.4
2,981,808	+				-0.3
2,981,809	-				-0.3
2,981,809	-				+0.0
2,981,809	-				+0.2
2,981,809	-				-0.3